PD-1 Protein (Fc-His Tag)
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- 抗原 See all PD-1 (PDCD1) 蛋白
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PD-1 protein is labelled with Fc-His Tag.
- 应用范围
- ELISA
- 原理
- Recombinant human PD-1 protein with C-terminal human Fc and 6xHis tag
- 特异性
- PD-1 (Leu25-Gln167) hFc (Glu99-Ala330) 6xHis tag
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- affinity purification
- 纯度
- The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product PDCD1 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with deionized water
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存液
- Without preservative
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
- 别名
- PD-1 (PDCD1 产品)
- 别名
- CD279 Protein, PD-1 Protein, PD1 Protein, SLEB2 Protein, hPD-1 Protein, hPD-l Protein, Ly101 Protein, Pdc1 Protein, programmed cell death 1 Protein, PDCD1 Protein, Pdcd1 Protein
- 背景
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Synonymes: PDCD1, PD1, CD279, SLEB2
Description: This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. - 分子量
- predicted molecular mass of 42.9 kDa after removal of the signal peptide.
- 基因ID
- 5133
- UniProt
- Q15116
- 途径
- Cancer Immune Checkpoints
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