KREMEN2 Protein (AA 26-364) (His tag)
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- 抗原 See all KREMEN2 蛋白
- KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 26-364
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This KREMEN2 protein is labelled with His tag.
- 原理
- Human Kremen-2 Protein
- 序列
- Gly26-Ala364
- 产品特性
- Recombinant Human Kremen-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly26-Ala364.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human Kremen-2, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-Kremen-2 Antibody, hFc Tag with the EC50 of 12.4ng/ml determined by ELISA. See testing image for detail.
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Kringle Containing Transmembrane Protein 2 (KREMEN2) (AA 26-364) protein (His tag)
KREMEN2 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Kringle Containing Transmembrane Protein 2 (KREMEN2) (AA 25-363) protein (His tag)KREMEN2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Kringle Containing Transmembrane Protein 2 (KREMEN2) (AA 1-420) protein (GST tag)KREMEN2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Kringle Containing Transmembrane Protein 2 (KREMEN2) (AA 121-220) protein (GST tag)KREMEN2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Kringle Containing Transmembrane Protein 2 (KREMEN2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)KREMEN2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
- 别名
- Kremen-2 (KREMEN2 产品)
- 别名
- krm2 Protein, KREMEN2 Protein, MGC147633 Protein, KRM2 Protein, 2900054E04Rik Protein, Krm2 Protein, kringle containing transmembrane protein 2 S homeolog Protein, kringle containing transmembrane protein 2 Protein, kremen2.S Protein, KREMEN2 Protein, kremen2 Protein, Kremen2 Protein
- 背景
- Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Compared to para-cancerous tissues, Krm2 was significantly up-regulated in gastric cancer tissues and was positively correlated with the pathological grade of gastric cancer patients. Krm2 can be a potent candidate for designing of targeted therapy.
- 分子量
- 37.1 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
- 途径
- WNT signaling
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