KREMEN2 蛋白
(Kringle Containing Transmembrane Protein 2 (KREMEN2))
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011].
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KREMEN2
宿主: 人
宿主: HEK-293 Cells
Recombinant
>95 % as determined by reduced SDS-PAGE.
Active
Aliases for KREMEN2 蛋白
kringle containing transmembrane protein 2 S homeolog (kremen2.S) 蛋白kringle containing transmembrane protein 2 (KREMEN2) 蛋白
kringle containing transmembrane protein 2 (kremen2) 蛋白
kringle containing transmembrane protein 2 (Kremen2) 蛋白
2900054E04Rik 蛋白
KREMEN2 蛋白
krm2 蛋白
KRM2 蛋白
Krm2 蛋白
MGC147633 蛋白
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