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CD226 Protein (CD226) (AA 19-247) (His-Avi Tag)

CD226 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
产品编号 ABIN7274455
发货至: 中国
  • 抗原 See all CD226 蛋白
    CD226
    蛋白类型
    Recombinant
    产品特性
    AA 19-247
    宿主
    • 21
    • 7
    • 2
    • 1
    • 1
    资源
    • 19
    • 5
    • 5
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This CD226 protein is labelled with His-Avi Tag.
    原理
    Human DNAM-1/CD226 Protein
    序列
    Glu19-Asn247
    产品特性
    Recombinant Human DNAM-1/CD226 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu19-Asn247.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 0.22μM as determined in SPR assay (Biacore T200). See testing image for detail.
    Top Product
    Discover our top product CD226 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    CD226
    别名
    DNAM-1 (CD226 产品)
    别名
    CD226 Protein, cd226 Protein, zgc:158817 Protein, BC051526 Protein, DNAM-1 Protein, DNAM1 Protein, Pta1 Protein, TLiSA1 Protein, PTA1 Protein, CD226 molecule Protein, CD226 antigen Protein, CD226 Protein, cd226 Protein, Cd226 Protein
    背景
    DNAX accessory molecule-1 (DNAM-1), also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily.DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.
    分子量
    28.9 kDa. Due to glycosylation, the protein migrates to 45-70 kDa based on Tris-Bis PAGE result.
    UniProt
    Q15762
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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