CD226 Protein (CD226) (AA 1-265) (Fc Tag)
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Quick Overview for CD226 Protein (CD226) (AA 1-265) (Fc Tag) (ABIN7321104)
抗原
See all CD226 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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产品特性
- AA 1-265
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标记
- This CD226 protein is labelled with Fc Tag.
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原理
- Recombinant Rat CD226/DNAM-1 Protein (Fc Tag)
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序列
- Met1-Ile265
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产品特性
- A DNA sequence encoding the rat CD226 (D3ZS97) (Met1-Ile265) was expressed with the Fc region of human IgG1 at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Immobilized rat PVR-His at 10 μg/ml (100 μl/well) can bind rat CD226-Fc, The EC50 of rat CD226-Fc is 0.41-0.97 μg/ml.
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CD226 (CD226) (AA 19-247) (Active) protein (His-Avi Tag)
CD226 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD226 (CD226) (AA 19-247) (Active) protein (Biotin,His-Avi Tag)CD226 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD226 (CD226) (AA 19-252) (Active) protein (His tag)CD226 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD226 (CD226) (AA 19-247) protein (His tag,mFc Tag)CD226 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
CD226 (CD226) (AA 19-252) (Active) protein (His tag)CD226 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
CD226 (CD226) (AA 19-254) protein (Fc Tag)CD226 宿主: 小鼠 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
CD226 (CD226) (AA 19-247) protein (hIgG-His-tag)CD226 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % SDS
CD226 (CD226) proteinCD226 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS
CD226 (CD226) (AA 19-254) protein (His tag)CD226 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
CD226 (CD226) (Active) protein (His tag)CD226 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by reducing SDS-PAGE. ELISA Active
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- CD226
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别名
- CD226/DNAM-1
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背景
- CD226,The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD226, also known as PTA1 or DNAM-1, is a member of the immunoglobulin superfamily containing 2 Ig-like domains of the V-set. High rate of CD226 (Cluster of Differentiation 226) is found on the surface of natural killer cells, platelets, monocytes and a subset of T cells. CD226 have binding sites with CD112 and CD155 and mediate cellular adhesion to other cells containing its ligands.
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分子量
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Calculated MW: 53.6 kDa
Observed MW: 62-68 kDa
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UniProt
- D3ZS97
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
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