CD226 Protein (CD226) (AA 19-254) (His tag)
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Quick Overview for CD226 Protein (CD226) (AA 19-254) (His tag) (ABIN7320734)
抗原
See all CD226 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 19-254
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标记
- This CD226 protein is labelled with His tag.
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原理
- Recombinant Mouse CD226/DNAM-1 Protein (His Tag)
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序列
- Glu19-Pro254
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产品特性
- Recombinant Mouse DNAX Accessory Molecule-1 is produced by our Mammalian expression system and the target gene encoding Glu19-Pro254 is expressed with a 6His tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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CD226 (CD226) (AA 19-247) (Active) protein (His-Avi Tag)
CD226 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD226 (CD226) (AA 19-247) (Active) protein (Biotin,His-Avi Tag)CD226 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD226 (CD226) (AA 19-252) (Active) protein (His tag)CD226 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD226 (CD226) (AA 19-247) protein (His tag,mFc Tag)CD226 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
CD226 (CD226) (AA 19-252) (Active) protein (His tag)CD226 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
CD226 (CD226) (AA 19-254) protein (Fc Tag)CD226 宿主: 小鼠 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
CD226 (CD226) (AA 19-247) protein (hIgG-His-tag)CD226 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % SDS
CD226 (CD226) proteinCD226 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS
CD226 (CD226) (Active) protein (His tag)CD226 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by reducing SDS-PAGE. ELISA Active
CD226 (CD226) (AA 1-265) (Active) protein (Fc Tag)CD226 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE. ELISA Active
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- CD226
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别名
- CD226/DNAM-1
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背景
- BC051526,CD226,CD226 antigen,CD226 Molecule,DNAM-1,DNAM1,DNAM1 adhesion glycoprotein,DNAX accessory molecule 1,DNAX accessory molecule-1,PTA1,Pta1,T lineage-specific activation antigen 1 antigen,TLiSA1,platelet and T cell activation antigen 1,Mouse DNAX accessory molecule-1(DNAM-1) is a type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily. As an activating receptor, it interacts with the ligands CD155 and CD112, and activates natural killer (NK) cells via its immu-noreceptor tyrosine-based activatory motif (ITAM). Mature mouse DNAM-1 has extracellular domain (ECD) that contains two Ig-like C2-set domains, and possesses a cytoplasmic region that contains motifs for binding PDZ domains. DNAM-1 is expressed on several lymphoid and myeloid cell types and interacts with CD155/PVR and Nectin-2/CD112. Ligation of DNAM-1 promotes the activation of NK cells, CD8+ T cells, and mast cells, induces dendritic cell maturation, initiates megakaryocyte and activated platelet adhesion to vascular endothelial cells, and stimulates monocyte extravasation. Conversely, it inhibits the formation of osteoclasts. Platelet-endothelium interactions that are mediated by DNAM-1 enable the metastasis of tumor cells to the lung.
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分子量
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Calculated MW: 27.6 kDa
Observed MW: 35-50 kDa
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NCBI登录号
- NP_848802
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
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