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LI Cadherin Protein (AA 23-667) (His tag)

宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
产品编号 ABIN7274308
发货至: 中国
  • 抗原 See all LI Cadherin 蛋白
    LI Cadherin
    蛋白类型
    Recombinant
    产品特性
    AA 23-667
    宿主
    • 20
    • 7
    • 3
    • 1
    • 1
    • 1
    资源
    • 21
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This LI Cadherin protein is labelled with His tag.
    原理
    Human CDH17/Cadherin 17 Domain 1-6 Protein
    序列
    Gln23-Leu667
    产品特性
    Recombinant Human CDH17/Cadherin 17 Domain 1-6 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln23-Leu667.
    纯度
    > 95 % as determined by Tris-Bis PAGE
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human CDH17 Domain 1-6, His Tag at 1_g/ml (100_l/Well) on the plate. Dose response curve for Anti-CDH17 Anitibody, hFc Tag with the EC50 of 7.3ng/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product LI Cadherin 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl ( pH 8.0).. Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    LI Cadherin
    别名
    CDH17 (LI Cadherin 产品)
    别名
    CDH16 Protein, HPT-1 Protein, HPT1 Protein, HPT-1/LI Protein, cb903 Protein, fb65d02 Protein, wu:fb65d02 Protein, cadherin-17 Protein, cadherin 17 Protein, cadherin 17, LI cadherin (liver-intestine) Protein, CDH17 Protein, Cdh17 Protein, cdh17 Protein
    背景
    Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
    分子量
    72.90 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
    UniProt
    Q12864
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