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LI Cadherin Protein (AA 1-795) (His tag)

宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
产品编号 ABIN7274303
发货至: 中国
  • 抗原 See all LI Cadherin 蛋白
    LI Cadherin
    蛋白类型
    Recombinant
    产品特性
    AA 1-795
    宿主
    • 21
    • 7
    • 3
    • 1
    • 1
    Cynomolgus
    资源
    • 21
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This LI Cadherin protein is labelled with His tag.
    原理
    Cynomolgus CDH17/Cadherin 17 Protein
    序列
    Met1-Met795
    产品特性
    Recombinant Cynomolgus CDH17/Cadherin 17 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Met1-Met795.
    纯度
    > 90 % as determined by Tris-Bis PAGE
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 13.30 nM as determined in SPR assay (Biacore T200). See testing image for detail.
    Top Product
    Discover our top product LI Cadherin 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS (PH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    LI Cadherin
    别名
    CDH17 (LI Cadherin 产品)
    别名
    CDH16 Protein, HPT-1 Protein, HPT1 Protein, HPT-1/LI Protein, cb903 Protein, fb65d02 Protein, wu:fb65d02 Protein, cadherin-17 Protein, cadherin 17 Protein, cadherin 17, LI cadherin (liver-intestine) Protein, CDH17 Protein, Cdh17 Protein, cdh17 Protein
    背景
    Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
    分子量
    89.2 kDa. Due to glycosylation, the protein migrates to 105-115 kDa based on Tris-Bis PAGE result.
    UniProt
    A0A2K5X8I8
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