LI Cadherin Protein (AA 23-787) (His tag)
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Quick Overview for LI Cadherin Protein (AA 23-787) (His tag) (ABIN7274306)
抗原
See all LI Cadherin 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 23-787
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标记
- This LI Cadherin protein is labelled with His tag.
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原理
- Human CDH17/Cadherin 17 Protein
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序列
- Gln23-Met787
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产品特性
- Recombinant Human CDH17/Cadherin 17 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gln23-Met787.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Human CDH17, His Tag at 1 ug/ml (100 ul/Well) on the plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 4.1 ng/ml determined by ELISA.,Human CDH17 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,Loaded Anti-CDH17 Ab., hFc Tag on ProA-Biosensor can bind Human CDH17, His Tag with an affinity constant of 2.26 nM as determined in BLI assay (Gator® Prime).
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LI Cadherin (AA 23-787) (Active) protein (hFc Tag)
宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
LI Cadherin (AA 23-787) (Active) protein (Biotin,His-Avi Tag)宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
LI Cadherin (AA 1-795) protein (His tag)宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
LI Cadherin (AA 30-244) (Active) protein (His tag)宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
LI Cadherin (AA 23-667) (Active) protein (His tag)宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
LI Cadherin (AA 567-777) (Active) protein (hFc Tag)宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
LI Cadherin (AA 23-787) (Active) protein (His tag,FITC)宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
LI Cadherin (AA 30-792) protein (His tag)宿主: Cynomolgus 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
LI Cadherin (AA 450-777) (Active) protein (His tag)宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
LI Cadherin (AA 24-131) protein (GST tag)宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.
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缓冲液
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- LI Cadherin
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别名
- CDH17
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背景
- Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
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分子量
- 86.1 kDa. Due to glycosylation, the protein migrates to 90-115 kDa based on Bis-Tris PAGE result.
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UniProt
- Q12864
抗原
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