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Fc epsilon RI/FCER1A Protein (His tag)

SPR verified FCER1A 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
产品编号 ABIN7271662
发货至: 中国
  • 抗原 See all Fc epsilon RI/FCER1A (FCER1A) 蛋白
    Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
    蛋白类型
    Recombinant
    宿主
    • 8
    • 5
    • 1
    • 1
    Cynomolgus
    资源
    • 8
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This Fc epsilon RI/FCER1A protein is labelled with His tag.
    原理
    Cynomolgus Fc epsilon RI alpha Protein, His Tag (SPR verified)
    序列
    Val 29 - Lys 204
    产品特性
    Cynomolgus Fc epsilon RI alpha, His Tag (FCA-C52H9) is expressed from human 293 cells (HEK293). It contains AA Val 29 - Lys 204 (Accession # A0A7N9DA09-1).
    纯度
    >90 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    质量等级
    SPR verified
    Top Product
    Discover our top product FCER1A 蛋白
  • 应用备注
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 22.3 kDa. The protein migrates as 35-55 kDa under reducing (R) condition due to glycosylation.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -20 °C
    储存方法
    -20°C
  • 抗原
    Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
    别名
    Fc epsilon RI alpha (FCER1A 产品)
    别名
    FCER1A Protein, FCE1A Protein, FcERI Protein, Iger01 Protein, RATIGER01 Protein, Fce1a Protein, Fcr-5 Protein, fcepsilonri Protein, Fc fragment of IgE receptor Ia Protein, Fc receptor, IgE, high affinity I, alpha polypeptide Protein, FCER1A Protein, Fcer1a Protein
    背景
    Synonyms:FCER1A,FCE1A,FcERI,Description:High affinity immunoglobulin epsilon receptor subunit alpha (FCER1A) is also known as Fc-epsilon RI-alpha (FcERI), IgE Fc receptor subunit alpha, FCE1A. FCER1A contains two Ig-like (immunoglobulin-like) domains. FCER1A binds to the Fc region of immunoglobulins epsilon and is a high affinity receptor. FCER1A is responsible for initiating the allergic response, which binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. FCER1A plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma.
    分子量
    22.3 kDa
    途径
    Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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