Fc epsilon RI/FCER1A Protein (AA 26-205) (His tag)
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Quick Overview for Fc epsilon RI/FCER1A Protein (AA 26-205) (His tag) (ABIN2181074)
抗原
See all Fc epsilon RI/FCER1A (FCER1A) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 26-205
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标记
- This Fc epsilon RI/FCER1A protein is labelled with His tag.
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序列
- AA 26-205
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产品特性
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 21.9 kDa. The protein migrates as 40-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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Fc Fragment of IgE Receptor Ia (FCER1A) (AA 26-205) (Active) protein (hFc Tag)
FCER1A 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Fc Fragment of IgE Receptor Ia (FCER1A) (AA 26-205) (Active) protein (His tag)FCER1A 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Fc Fragment of IgE Receptor Ia (FCER1A) (AA 24-204) (Active) protein (hFc Tag)FCER1A 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Fc Fragment of IgE Receptor Ia (FCER1A) (AA 26-205) protein (His tag)FCER1A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Fc Fragment of IgE Receptor Ia (FCER1A) (AA 1-257) protein (GST tag)FCER1A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fc Fragment of IgE Receptor Ia (FCER1A) protein (Fc Tag)FCER1A 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, pH 7.4
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注意事项
- Please avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
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别名
- FCER1A
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背景
- High affinity immunoglobulin epsilon receptor subunit alpha (FCER1A) is also known as Fc-epsilon RI-alpha (FcERI), IgE Fc receptor subunit alpha, FCE1A. FCER1A contains two Ig-like (immunoglobulin-like) domains. FCER1A binds to the Fc region of immunoglobulins epsilon and is a high affinity receptor. FCER1A is responsible for initiating the allergic response, which binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. FCER1A plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma.
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分子量
- 22.9 kDa
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途径
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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