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TNFRSF13C Protein (His tag)

TNFRSF13C 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
产品编号 ABIN7321204
发货至: 中国
  • 抗原 See all TNFRSF13C 蛋白
    TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
    蛋白类型
    Recombinant
    宿主
    • 19
    • 8
    • 2
    • 2
    大鼠
    资源
    • 21
    • 4
    • 2
    • 2
    HEK-293 Cells
    标记
    This TNFRSF13C protein is labelled with His tag.
    原理
    Recombinant Rat BAFFR/TNFRSF13C Protein (His Tag)
    序列
    Ser10-Ala71
    产品特性
    A DNA sequence encoding the rat TNFRSF13C (D3ZNT3) (Ser10-Ala71) was expressed with a polyhistidine tag at the C-terminus.
    纯度
    > 85 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method
    Top Product
    Discover our top product TNFRSF13C 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
    别名
    BAFFR/TNFRSF13C (TNFRSF13C 产品)
    别名
    RGD1560810 Protein, TNFRSF13C Protein, BAFF-R Protein, BAFFR Protein, BROMIX Protein, CD268 Protein, CVID4 Protein, prolixin Protein, 2010006P15Rik Protein, Baffr Protein, Bcmd Protein, Bcmd-1 Protein, Bcmd1 Protein, Lvis22 Protein, TNF receptor superfamily member 13C Protein, uncharacterized LOC746611 Protein, tumor necrosis factor receptor superfamily, member 13c Protein, TNFRSF13C Protein, Tnfrsf13c Protein, LOC746611 Protein
    背景

    Background: Tumor necrosis factor receptor superfamily, member 13C (TNFRSF13C) also known as B-cell-activating factor receptor (BAFFR) and CD268 antigen, is a member of the tumor necrosis factor receptor superfamily. A tumor necrosis factor receptor (TNFR), or death receptor, is a trimeric cytokine receptor that binds tumor necrosis factors (TNF). The receptor cooperates with an adaptor protein which is important in determining the outcome of the response. Members of the TNF receptor superfamily (TNFRSF) have crucial roles in both innate and adaptive immunity and in cellular apoptosis process. Apoptosis is a cell suicide mechanism that enables metazoans to control cell number in tissues and to eliminate individual cells that threaten the animal's survival. Certain cells have unique sensors, termed death receptors or tumour necrosis factor (TNFR), on their surface. Tumour necrosis factors (TNFR) detect the presence of extracellular death signals and, in response, they rapidly ignite the cell's intrinsic apoptosis machinery. It has been proposed that abnormally high levels of BAFFR/TNFRSF13C (CD268) may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.

    Synonym: TNFRSF13C

    分子量
    8.3 kDa
    UniProt
    D3ZNT3
    途径
    NF-kappaB Signaling
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