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TNFRSF13C Protein (mFc Tag)

TNFRSF13C 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
产品编号 ABIN6961114
发货至: 中国
  • 抗原 See all TNFRSF13C 蛋白
    TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
    蛋白类型
    Recombinant
    宿主
    • 18
    • 8
    • 3
    • 2
    资源
    • 21
    • 4
    • 2
    • 2
    HEK-293 Cells
    标记
    This TNFRSF13C protein is labelled with mFc Tag.
    应用范围
    ELISA
    原理
    Recombinant Human BAFF-R protein with C-terminal mouse Fc
    特异性
    BAFF-R (Ser7-Ala71) mFc (Pro99-Lys330)
    产品特性
    Extracellular Domain Protein
    纯化方法
    affinity purification
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Biological Activity Comment
    EC50=109.8
    Top Product
    Discover our top product TNFRSF13C 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存液
    Without preservative
    储存条件
    -20 °C,-80 °C
    有效期
    12 months
  • 抗原
    TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
    别名
    BAFF-R (TNFRSF13C 产品)
    别名
    RGD1560810 Protein, TNFRSF13C Protein, BAFF-R Protein, BAFFR Protein, BROMIX Protein, CD268 Protein, CVID4 Protein, prolixin Protein, 2010006P15Rik Protein, Baffr Protein, Bcmd Protein, Bcmd-1 Protein, Bcmd1 Protein, Lvis22 Protein, TNF receptor superfamily member 13C Protein, uncharacterized LOC746611 Protein, tumor necrosis factor receptor superfamily, member 13c Protein, TNFRSF13C Protein, Tnfrsf13c Protein, LOC746611 Protein
    背景
    Synonymes: BAFFR,TNFRSF13C,BAFF-R,BROMIX,CD268,CVID4,prolixin
    Description: B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
    分子量
    predicted molecular mass of 33.6 kDa after removal of the signal peptide.The apparent molecular mass of BAFF-R-mFc is 35-55 kDa due to glycosylation.
    基因ID
    115650
    UniProt
    Q96RJ3
    途径
    NF-kappaB Signaling
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