PDCD1LG2 Protein (Fc Tag)
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- 抗原 See all PDCD1LG2 蛋白
- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This PDCD1LG2 protein is labelled with Fc Tag.
- 原理
- Recombinant Mouse B7-DC/PD-L2/CD273 Protein (Fc Tag)(Active)
- 序列
- Met 1-Arg 219
- 产品特性
- A DNA sequence encoding the extracellular domain of mouse PDCD1LG2 (Q9WUL5) (Met 1-Arg 219) was fused with the Fc region of human IgG1 at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- 1. Measured by its binding ability in a functional ELISA.2. Immobilized human PD1-His at 10 μg/mL (100 μl/well) can bind mouse PD-L2-Fc, The EC50 of mouse PD-L2-Fc is 0.95 μg/mL.
- Top Product
- Discover our top product PDCD1LG2 蛋白
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Programmed Cell Death 1 Ligand 2 (PDCD1LG2) protein (His-Avi Tag)
PDCD1LG2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-220) protein (His tag)PDCD1LG2 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-220) protein (His-Avi Tag,Biotin)PDCD1LG2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-219) (Active) protein (Fc Tag)PDCD1LG2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 19-121) protein (His-DYKDDDDK-Strep II Tag)PDCD1LG2 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 19-220) protein (His-DYKDDDDK-Strep II Tag)PDCD1LG2 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-219) (Active) protein (His tag)PDCD1LG2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-219) protein (His tag)PDCD1LG2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-219) (Active) protein (His tag,AVI tag,Biotin)PDCD1LG2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) protein (Fc Tag)PDCD1LG2 宿主: Cynomolgus 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
- 别名
- B7-DC/PD-L2/CD273 (PDCD1LG2 产品)
- 别名
- PDL2 Protein, B7DC Protein, Btdc Protein, CD273 Protein, PD-L2 Protein, PDCD1L2 Protein, bA574F11.2 Protein, B7-DC Protein, F730015O22Rik Protein, programmed cell death 1 ligand 2 Protein, PDCD1LG2 Protein, Pdcd1lg2 Protein
- 背景
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Background: Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally consists of an extracellular region containing one V-like and one C-like Ig domain, a transmembrane region, and a short cytoplasmic domain. PD-L2 is expressed on antigen presenting cells, placental endothelium and medullary thymic epithelial cells, and can be induced by LPS in B cells, INF-γ in monocytes, or LPS plus IFN-γ in dendritic cells. The CD28 and B7 protein families are critical regulators of immune responses. PD-L2 and PD-L1 are two ligands for PD-1, member of the CD28/CTLA4 family expressed on activated lymphoid cells, and thus provide signals for regulating T cell activation and immune tolerance. The interaction of B7-DC/PD-1 exhibited a 2-6-fold higher affinity compared with the interaction of B7-H1/PD-1.Immune CheckpointImmune Checkpoint Detection: Antibodies Immune Checkpoint Detection: ELISA Antibodies Immune Checkpoint Detection: FCM Antibodies Immune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint Targets Co-inhibitory Immune Checkpoint Targets Immunotherapy Cancer Immunotherapy Targeted Therapy
Synonym: Programmed cell death 1 ligand 2;Pdcd1lg2;PD-1 ligand 2;PD-L2; PDCD1 ligand 2; B7-DC; CD273;Btdc;F730015O22Rik;PD-L2
- 分子量
- 49.5 kDa
- UniProt
- Q9WUL5
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