PDCD1LG2 Protein (AA 20-219) (His tag,AVI tag,Biotin)
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- 抗原 See all PDCD1LG2 蛋白
- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 20-219
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PDCD1LG2 protein is labelled with His tag,AVI tag,Biotin.
- 品牌
- MABSol®,PrecisionAvi
- 序列
- AA 20-219
- 特异性
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- 产品特性
- This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 25.2 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product PDCD1LG2 蛋白
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Programmed Cell Death 1 Ligand 2 (PDCD1LG2) protein (His-Avi Tag)
PDCD1LG2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-220) protein (His tag)PDCD1LG2 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-220) protein (His-Avi Tag,Biotin)PDCD1LG2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-219) (Active) protein (Fc Tag)PDCD1LG2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 19-121) protein (His-DYKDDDDK-Strep II Tag)PDCD1LG2 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 19-220) protein (His-DYKDDDDK-Strep II Tag)PDCD1LG2 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-219) (Active) protein (His tag)PDCD1LG2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-219) protein (His tag)PDCD1LG2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) protein (Fc Tag)PDCD1LG2 宿主: Cynomolgus 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-220) protein (His tag)PDCD1LG2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- 说明
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Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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: "In Vitro Assays to Study PD-1 Biology in Human T Cells." in: Current protocols in immunology, Vol. 130, Issue 1, pp. e103, (2020) (PubMed).
: "In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy." in: Science translational medicine, Vol. 9, Issue 389, (2018) (PubMed).
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: "In Vitro Assays to Study PD-1 Biology in Human T Cells." in: Current protocols in immunology, Vol. 130, Issue 1, pp. e103, (2020) (PubMed).
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- 抗原
- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
- 别名
- PD-L2 (PDCD1LG2 产品)
- 别名
- PDL2 Protein, B7DC Protein, Btdc Protein, CD273 Protein, PD-L2 Protein, PDCD1L2 Protein, bA574F11.2 Protein, B7-DC Protein, F730015O22Rik Protein, programmed cell death 1 ligand 2 Protein, PDCD1LG2 Protein, Pdcd1lg2 Protein
- 背景
- Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
- 分子量
- 25.2 kDa
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