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PDCD1LG2 Protein (AA 20-219) (His tag)

PDCD1LG2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
产品编号 ABIN2870761
发货至: 中国
  • 抗原 See all PDCD1LG2 蛋白
    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
    蛋白类型
    Recombinant
    产品特性
    AA 20-219
    宿主
    • 30
    • 11
    • 2
    • 2
    小鼠
    资源
    • 25
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This PDCD1LG2 protein is labelled with His tag.
    序列
    AA 20-219
    产品特性
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 24.4 kDa. The protein migrates as 37-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product PDCD1LG2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
  • 抗原
    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
    别名
    PD-L2 (PDCD1LG2 产品)
    别名
    PDL2 Protein, B7DC Protein, Btdc Protein, CD273 Protein, PD-L2 Protein, PDCD1L2 Protein, bA574F11.2 Protein, B7-DC Protein, F730015O22Rik Protein, programmed cell death 1 ligand 2 Protein, PDCD1LG2 Protein, Pdcd1lg2 Protein
    背景
    Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
    分子量
    24.4 kDa
    NCBI登录号
    NP_067371
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