PDCD1LG2 Protein (His-Avi Tag)
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- 抗原 See all PDCD1LG2 蛋白
- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PDCD1LG2 protein is labelled with His-Avi Tag.
- 序列
- Leu20-Thr220
- 纯度
- > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.296 μM as determined in SPR assay (Biacore T200). See testing image for detail.
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Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-220) protein (His tag)
PDCD1LG2 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-220) protein (His-Avi Tag,Biotin)PDCD1LG2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-219) (Active) protein (Fc Tag)PDCD1LG2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 19-121) protein (His-DYKDDDDK-Strep II Tag)PDCD1LG2 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 19-220) protein (His-DYKDDDDK-Strep II Tag)PDCD1LG2 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-219) (Active) protein (His tag)PDCD1LG2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-219) protein (His tag)PDCD1LG2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-219) (Active) protein (His tag,AVI tag,Biotin)PDCD1LG2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) protein (Fc Tag)PDCD1LG2 宿主: Cynomolgus 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-220) protein (His tag)PDCD1LG2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
- 别名
- PD-L2 (PDCD1LG2 产品)
- 别名
- PDL2 Protein, B7DC Protein, Btdc Protein, CD273 Protein, PD-L2 Protein, PDCD1L2 Protein, bA574F11.2 Protein, B7-DC Protein, F730015O22Rik Protein, programmed cell death 1 ligand 2 Protein, PDCD1LG2 Protein, Pdcd1lg2 Protein
- 背景
- PDL2, PD-L2, Butyrophilin B7-DC, CD273, PDCD1 ligand 2, PDCD1L2, PDCD1LG2, B7DC, bA574F11.2, Btdc,PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals.
- 分子量
- 25.3 kDa. Due to glycosylation, the protein migrates to 40-52 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9BQ51
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