KLRK1 Protein (His tag)
-
- 抗原 See all KLRK1 蛋白
- KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
-
宿主
- 人
-
资源
- 人细胞
- 标记
- This KLRK1 protein is labelled with His tag.
- 原理
- Recombinant Human NKG2D/CD314 Protein (His Tag)(Active)
- 序列
- Phe78-Val216
- 产品特性
- Recombinant Human NKG2-D type II Integral Membrane Protein is produced by our Mammalian expression system and the target gene encoding Phe78-Val216 is expressed with a 6His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human NKG2D-His at 10μg/ml(100 μl/well) can bind Human MICA-Fc(Cat: PKSH032753). The ED50 of Human NKG2D-His is 19.8 ug/ml .
- Top Product
- Discover our top product KLRK1 蛋白
-
Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 78-216) protein (Fc-DYKDDDDK Tag)
KLRK1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 78-216) protein (His-Avi Tag)KLRK1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 73-216) protein (His tag)KLRK1 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) protein (mFc Tag)KLRK1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) protein (His-Avi Tag,Biotin)KLRK1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 90-232) protein (His tag)KLRK1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 90-232) protein (Fc Tag)KLRK1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 73-216) (Active) protein (Fc Tag)KLRK1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 1-216) protein (GST tag)KLRK1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 73-216) (Active) protein (mFc Tag)KLRK1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))
- 别名
- NKG2D/CD314 (KLRK1 产品)
- 别名
- KLRK1 Protein, NKG2D Protein, CD314 Protein, D12S2489E Protein, KLR Protein, NKG2-D Protein, D6H12S2489E Protein, Nkg2d Protein, Nkrp2 Protein, killer cell lectin like receptor K1 Protein, killer cell lectin-like receptor subfamily K, member 1 Protein, NKG2D protein Protein, KLRK1 Protein, Klrk1 Protein, NKG2D Protein
- 背景
-
Background: NKG2-D type II integral membrane protein (NKG2D) is a type II transmembrane glycoprotein which belongs to the CD94/NKG2 family. NKG2D is expressed on natural killer (NK) cells, CD8+ alpha-beta and gamma-delta T-cells. As an activating and costimulatory receptor, it involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. It provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. It stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF-alpha. NKG2D participates in NK cell-mediated bone marrow graft rejection and survival of NK cells. It Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins including MICA, MICB, RAET1E, RAET1G, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4.
Synonym: CD314, KLRK1,CD314 antigen,Killer cell lectin-like receptor subfamily K member 1, killer cell lectin-like receptor subfamily K, member 1, KLR, NK cell receptor D, NKG2-D, NKG2-D type II integral membrane protein, NKG2-D-activating NK recepto
- 分子量
- 16.9 kDa
- UniProt
- P26718
- 途径
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
-
