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KLRK1 Protein (AA 78-216) (His-Avi Tag)

KLRK1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
产品编号 ABIN7275342
发货至: 中国
  • 抗原 See all KLRK1 蛋白
    KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))
    蛋白类型
    Recombinant
    产品特性
    AA 78-216
    宿主
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    资源
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    HEK-293 Cells
    标记
    This KLRK1 protein is labelled with His-Avi Tag.
    原理
    Human NKG2D/CD314 Protein
    序列
    Phe78-Val216
    产品特性
    Recombinant Human NKG2D/CD314 Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Phe78-Val216.
    纯度
    > 95 % as determined by Tris-Bis PAGE
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human NKG2D, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-NKG2D Antibody, hFc Tag with the EC50 of 12.2ng/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product KLRK1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))
    别名
    NKG2D (KLRK1 产品)
    别名
    KLRK1 Protein, NKG2D Protein, CD314 Protein, D12S2489E Protein, KLR Protein, NKG2-D Protein, D6H12S2489E Protein, Nkg2d Protein, Nkrp2 Protein, killer cell lectin like receptor K1 Protein, killer cell lectin-like receptor subfamily K, member 1 Protein, NKG2D protein Protein, KLRK1 Protein, Klrk1 Protein, NKG2D Protein
    背景
    NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate ligands. Human NKG2D is expressed on CD8 alpha beta T cells, gamma δ T cells, NK cells and NKT cells.
    分子量
    19.0 kDa. Due to glycosylation, the protein migrates to 36-38 kDa based on Tris-Bis PAGE result.
    UniProt
    P26718
    途径
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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