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IL15RA Protein (Fc Tag)

IL15RA 宿主: 小鼠 宿主: 人细胞 Recombinant > 90 % as determined by SDS-PAGE Active
产品编号 ABIN7320556
发货至: 中国
  • 抗原 See all IL15RA 蛋白
    IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 16
    • 5
    • 1
    小鼠
    资源
    • 11
    • 4
    • 3
    • 2
    • 1
    • 1
    人细胞
    标记
    This IL15RA protein is labelled with Fc Tag.
    原理
    Recombinant Mouse IL15RA/CD215 Protein (Fc Tag)(Active)
    序列
    Gly33-Lys205
    产品特性
    Recombinant Mouse Interleukin-15 receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Gly33-Lys205 is expressed with a Fc tag at the C-terminus.
    纯度
    > 90 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Measured by its ability to block human IL-15-induced proliferation of CTLL-2 mouse cytotoxic T cells. The ED50 for this effect is 0.5-2 ng/ml.
    Top Product
    Discover our top product IL15RA 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
    别名
    IL15RA/CD215 (IL15RA 产品)
    别名
    IL15RA Protein, CD215 Protein, AA690181 Protein, IL-15RA Protein, interleukin 15 receptor subunit alpha Protein, interleukin 15 receptor, alpha chain Protein, IL15RA Protein, Il15ra Protein
    背景

    Background: Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il15ra shares 45 % amino acid sequence homology with the mouse form of the receptor. Eight isoforms of IL-15 R alpha mRNA have been identified, resulting from alternative splicing events involving different exons.

    Synonym: Interleukin-15 receptor subunit alpha,Il15ra,sIL-15 receptor subunit alpha

    分子量
    45.5 kDa
    UniProt
    Q60819
    途径
    JAK/STAT Signaling
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