IL15RA Protein (Fc Tag)
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- 抗原 See all IL15RA 蛋白
- IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- 人细胞
- 标记
- This IL15RA protein is labelled with Fc Tag.
- 原理
- Recombinant Mouse IL15RA/CD215 Protein (Fc Tag)(Active)
- 序列
- Gly33-Lys205
- 产品特性
- Recombinant Mouse Interleukin-15 receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Gly33-Lys205 is expressed with a Fc tag at the C-terminus.
- 纯度
- > 90 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to block human IL-15-induced proliferation of CTLL-2 mouse cytotoxic T cells. The ED50 for this effect is 0.5-2 ng/ml.
- Top Product
- Discover our top product IL15RA 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
- 别名
- IL15RA/CD215 (IL15RA 产品)
- 别名
- IL15RA Protein, CD215 Protein, AA690181 Protein, IL-15RA Protein, interleukin 15 receptor subunit alpha Protein, interleukin 15 receptor, alpha chain Protein, IL15RA Protein, Il15ra Protein
- 背景
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Background: Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il15ra shares 45 % amino acid sequence homology with the mouse form of the receptor. Eight isoforms of IL-15 R alpha mRNA have been identified, resulting from alternative splicing events involving different exons.
Synonym: Interleukin-15 receptor subunit alpha,Il15ra,sIL-15 receptor subunit alpha
- 分子量
- 45.5 kDa
- UniProt
- Q60819
- 途径
- JAK/STAT Signaling
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