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IL15RA Protein (AA 31-205) (Fc Tag,AVI tag,Biotin)

IL15RA 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN6731258
发货至: 中国
  • 抗原 See all IL15RA 蛋白
    IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 31-205
    宿主
    • 16
    • 6
    • 1
    资源
    • 10
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This IL15RA protein is labelled with Fc Tag,AVI tag,Biotin.
    序列
    AA 31-205
    特异性
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL15RA 蛋白
  • 说明

    Ready-to-use AvitagTM biotinylated protein:
    The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
  • 抗原
    IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
    别名
    IL-15 R alpha (IL15RA 产品)
    别名
    IL15RA Protein, CD215 Protein, AA690181 Protein, IL-15RA Protein, interleukin 15 receptor subunit alpha Protein, interleukin 15 receptor, alpha chain Protein, IL15RA Protein, Il15ra Protein
    背景
    IL15R is a heterotrimer of IL15RA, IL2RB and IL2RG. IL-15RA, also known as CD215, IL-15 R alpha, is a widely expressed 60 kDa transmembrane glycoprotein. High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. An interleukin (IL)-15 superagonist/IL-15 receptor α fusion complex (IL-15SA/IL-15RA, ALT-803) activates the IL-15 receptor on CD8 T cells and NK cells, and has shown significant anti-tumor. Signal transduction involves SYK. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures.
    分子量
    46.6 kDa
    NCBI登录号
    NP_002180
    途径
    JAK/STAT Signaling
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