IL15RA 产品
(Interleukin 15 Receptor, alpha (IL15RA))
Categories
This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.[provided by RefSeq, Apr 2010].
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Featured IL15RA Categories
IL15RA 抗体
High quality antibodies with extensive validation data.
IL15RA ELISA试剂盒
Reliable ELISA kits for a wide range of species.
IL15RA 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IL15RA 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, Neut, ICC
Validations
- (4)
Cat. No.
ABIN7193409
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN1680439
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7242230
Quantity
200 μL
Datasheet
Datasheet
Recommended IL15RA ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967877
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967876
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1889338
Quantity
96 tests
Datasheet
Datasheet
Recommended IL15RA 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275020
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274956
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274957
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our IL15RA Products
: "NK Cells Require Cell-Extrinsic and -Intrinsic TYK2 for Full Functionality in Tumor Surveillance and Antibacterial Immunity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 202, Issue 6, pp. 1724-1734, (2019) (PubMed).: "Rheumatoid arthritis bone marrow environment supports Th17 response." in: Arthritis research & therapy, Vol. 19, Issue 1, pp. 274, (2018) (PubMed).
: "IL-15 signaling promotes adoptive effector T-cell survival and memory formation in irradiation-induced lymphopenia." in: Cell & bioscience, Vol. 6, pp. 30, (2016) (PubMed).
: "IL-18Rα-deficient CD4(+) T cells induce intestinal inflammation in the CD45RB(hi) transfer model of colitis despite impaired innate responsiveness." in: European journal of immunology, Vol. 46, Issue 6, pp. 1371-82, (2016) (PubMed).
: "IL-15 receptor α signaling constrains the development of IL-17-producing γδ T cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 31, pp. 9692-7, (2015) (PubMed).
: "Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 6, pp. 2818-28, (2015) (PubMed).
: "Intramuscular delivery of heterodimeric IL-15 DNA in macaques produces systemic levels of bioactive cytokine inducing proliferation of NK and T cells." in: Gene therapy, Vol. 22, Issue 1, pp. 76-86, (2015) (PubMed).
: "Interleukin-15 and soluble interleukin-15 receptor ? in coronary artery disease patients: association with epicardial fat and indices of adipose tissue distribution." in: PLoS ONE, Vol. 9, Issue 3, pp. e90960, (2014) (PubMed).
: "Anti-inflammatory cytokines directly inhibit innate but not adaptive CD8+ T cell functions." in: Journal of virology, Vol. 88, Issue 13, pp. 7474-84, (2014) (PubMed).
: "Regulation of CD4(+)NKG2D(+) Th1 cells in patients with metastatic melanoma treated with sorafenib: role of IL-15Rα and NKG2D triggering. ..." in: Cancer research, Vol. 74, Issue 1, pp. 68-80, (2014) (PubMed).
Synonyms and alternative names related to IL15RA
interleukin 15 receptor subunit alpha (IL15RA), interleukin 15 receptor subunit alpha (Il15ra), interleukin 15 receptor, alpha chain (Il15ra), AA690181, CD215, IL-15RA, IL15RAProtein level used designations for IL15RA
- interleukin-15 receptor subunit alpha
- interleukin 15 receptor alpha
- interleukin 15 receptor, alpha
- interleukin 15 receptor, alpha chain
- IL-15 receptor subunit alpha
- IL-15R-alpha
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