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IL17RA 产品

(Interleukin 17 Receptor A (IL17RA))

Categories

Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor\; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. [provided by RefSeq, Jul 2008].

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Featured IL17RA Categories

IL17RA 抗体

High quality antibodies with extensive validation data.

IL17RA ELISA试剂盒

Reliable ELISA kits for a wide range of species.

IL17RA 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IL17RA 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7438775
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS, Neut
Validations
  • (4)
Cat. No. ABIN7193333
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7437773
Quantity 100 μL
Datasheet Datasheet

Recommended IL17RA ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967893
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957051
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN625015
Quantity 96 tests
Datasheet Datasheet

Recommended IL17RA 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (6)
Cat. No. ABIN7274244
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
Cat. No. ABIN7274907
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274230
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our IL17RA Products

Zhang, Wang, Wang, Wang, Roden, Zhao, Li, Prakash, Matteson, Tschumperlin, Vassallo et al.: "Profibrotic effect of IL-17A and elevated IL-17RA in idiopathic pulmonary fibrosis and rheumatoid arthritis-associated lung disease support a direct role for IL-17A/IL-17RA in human fibrotic ..." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 316, Issue 3, pp. L487-L497, (2019) (PubMed).

Akbay, Koyama, Liu, Dries, Bufe, Silkes, Alam, Magee, Jones, Jinushi, Kulkarni, Carretero, Wang, Warner-Hatten, Cavanaugh, Osa, Kumanogoh, Freeman, Awad, Christiani, Bueno, Hammerman, Dranoff, Wong: "Interleukin-17A Promotes Lung Tumor Progression through Neutrophil Attraction to Tumor Sites and Mediating Resistance to PD-1 Blockade." in: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Vol. 12, Issue 8, pp. 1268-1279, (2018) (PubMed).

Tusi, Wolock, Weinreb, Hwang, Hidalgo, Zilionis, Waisman, Huh, Klein, Socolovsky: "Population snapshots predict early haematopoietic and erythroid hierarchies." in: Nature, Vol. 555, Issue 7694, pp. 54-60, (2018) (PubMed).

Koslawsky, Zaretsky, Alcalay, Mazor, Aharoni, Papo: "A bi-specific inhibitor targeting IL-17A and MMP-9 reduces invasion and motility in MDA-MB-231 cells." in: Oncotarget, Vol. 9, Issue 47, pp. 28500-28513, (2018) (PubMed).

Sebastian, Kannan, Norazmi, Nurul: "Interleukin-17A promotes osteogenic differentiation by increasing OPG/RANKL ratio in stem cells from human exfoliated deciduous teeth (SHED)." in: Journal of tissue engineering and regenerative medicine, Vol. 12, Issue 8, pp. 1856-1866, (2018) (PubMed).

Yan, Li, Yang, Zhang, Yang, Wang, Li: "Interleukin-17A participates in podocyte injury by inducing IL-1β secretion through ROS-NLRP3 inflammasome-caspase-1 pathway." in: Scandinavian journal of immunology, Vol. 87, Issue 4, pp. e12645, (2018) (PubMed).

Zhang, Zhou, Chen, Yang, Shi: "Identification of hub genes and pathways associated with bladder cancer based on co-expression network analysis." in: Oncology letters, Vol. 14, Issue 1, pp. 1115-1122, (2017) (PubMed).

Qiu, Liu, Wang: "Blocking IL-17A Alleviates Diabetic Retinopathy in Rodents." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 41, Issue 3, pp. 960-972, (2017) (PubMed).

Ganesan, Rasool: "Interleukin 17 regulates SHP-2 and IL-17RA/STAT-3 dependent Cyr61, IL-23 and GM-CSF expression and RANKL mediated osteoclastogenesis by fibroblast-like synoviocytes in rheumatoid arthritis." in: Molecular immunology, Vol. 91, pp. 134-144, (2017) (PubMed).

Tang, Tao, Lu, Tang, Shi: "Role of T helper 17 cytokines in the tumour immune inflammation response of patients with laryngeal squamous cell carcinoma." in: Oncology letters, Vol. 14, Issue 1, pp. 561-568, (2017) (PubMed).

Synonyms and alternative names related to IL17RA

interleukin 17 receptor A (IL17RA), interleukin 17 receptor A (Il17ra), AW538159, CANDF5, CD217, CDw217, Cdw217, hIL-17R, IL-17RA, IL17R, Il17r, VDw217

Protein level used designations for IL17RA

  • IL-17 receptor A
  • interleukin-17 receptor A
  • IL-17RA
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