IL15RA Protein (AA 31-205) (Fc Tag)
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- 抗原 See all IL15RA 蛋白
- IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 31-205
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL15RA protein is labelled with Fc Tag.
- 序列
- AA 31-205
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL15RA 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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- 抗原
- IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
- 别名
- IL-15 R alpha (IL15RA 产品)
- 别名
- IL15RA Protein, CD215 Protein, AA690181 Protein, IL-15RA Protein, interleukin 15 receptor subunit alpha Protein, interleukin 15 receptor, alpha chain Protein, IL15RA Protein, Il15ra Protein
- 背景
- IL15R is a heterotrimer of IL15RA, IL2RB and IL2RG. IL-15RA, also known as CD215, IL-15 R alpha, is a widely expressed 60 kDa transmembrane glycoprotein. High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. An interleukin (IL)-15 superagonist/IL-15 receptor α fusion complex (IL-15SA/IL-15RA, ALT-803) activates the IL-15 receptor on CD8 T cells and NK cells, and has shown significant anti-tumor. Signal transduction involves SYK. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures.
- 分子量
- 44.8 kDa
- NCBI登录号
- NP_002180
- 途径
- JAK/STAT Signaling
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