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Growth Hormone Receptor Protein (GHR) (Fc Tag)

GHR 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320745
发货至: 中国
  • 抗原 See all Growth Hormone Receptor (GHR) 蛋白
    Growth Hormone Receptor (GHR)
    蛋白类型
    Recombinant
    宿主
    • 16
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    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
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    小鼠
    资源
    • 14
    • 13
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    人细胞
    标记
    This Growth Hormone Receptor protein is labelled with Fc Tag.
    原理
    Recombinant Mouse Growth Hormone Receptor/GHR Protein (Fc Tag)
    序列
    Met1-Gln273
    产品特性
    Recombinant Mouse Growth Hormone receptor is produced by our Mammalian expression system and the target gene encoding Met1-Gln273 is expressed with a Fc tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product GHR 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Growth Hormone Receptor (GHR)
    别名
    Growth Hormone Receptor/GHR (GHR 产品)
    别名
    GHBP Protein, AA986417 Protein, GHR/BP Protein, GHR Protein, ghr Protein, ghr.a Protein, zgc:162141 Protein, growth hormone receptor Protein, growth hormone receptor L homeolog Protein, growth hormone receptor a Protein, GHR Protein, Ghr Protein, ghr.L Protein, ghr Protein, ghra Protein
    背景

    Background: Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Growth hormone receptor has been shown to interact with SGTA, PTPN11, Janus kinase 2, Suppressor of cytokine signaling 1 and CISH.

    Synonym: growth hormone binding protein, growth hormone receptor, serum binding protein, Somatotropin receptor,GHR, GH receptor, GHBP

    分子量
    58.3 kDa
    UniProt
    Q3UP14
    途径
    NF-kappaB Signaling, JAK/STAT Signaling, Response to Growth Hormone Stimulus
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