GAS6 Protein (His tag)
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- 抗原 See all GAS6 蛋白
- GAS6 (Growth Arrest-Specific 6 (GAS6))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 人细胞
- 标记
- This GAS6 protein is labelled with His tag.
- 原理
- Recombinant Human GAS6 (C-6His)
- 序列
- Ala31-Ala678
- 产品特性
- Recombinant Human Growth Arrest-specific Protein 6 is produced by our Mammalian expression system and the target gene encoding Ala31-Ala678 is expressed with a 6His tag at the C-terminus.
- 纯度
- >95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human AXL-His (Cat#C02B) at 10μg/ml (100 μl/well) can bind Human GAS6-His* (Cat#C01W).*: Biotinylated by NHS-biotin prior to testing.The ED50 of Recombinant Human GAS6-His* (Cat#C01W) is 0.04466 ug/ml.
- Top Product
- Discover our top product GAS6 蛋白
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Growth Arrest-Specific 6 (GAS6) (AA 31-637) protein (His tag)
GAS6 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Arrest-Specific 6 (GAS6) (AA 49-678) protein (His tag)GAS6 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Arrest-Specific 6 (GAS6) (AA 1-678) protein (GST tag)GAS6 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Growth Arrest-Specific 6 (GAS6) (AA 579-678) protein (GST tag)GAS6 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Growth Arrest-Specific 6 (GAS6) (AA 31-721) protein (His tag)Crystallography grade GAS6 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Growth Arrest-Specific 6 (GAS6) (AA 28-674) protein (His tag)Crystallography grade GAS6 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Growth Arrest-Specific 6 (GAS6) (AA 136-311) (Active) protein (His tag)GAS6 宿主: 人 宿主: 大肠杆菌（E. Coli） > 90 % AcA, CC Active
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of PBS, 10 % Glycerol, pH 7.4.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- GAS6 (Growth Arrest-Specific 6 (GAS6))
- 别名
- GAS6 (GAS6 产品)
- 别名
- fj34a12 Protein, zgc:63860 Protein, wu:fj34a12 Protein, MGC68463 Protein, gas6 Protein, MGC83872 Protein, GAS6 Protein, Gas-6 Protein, AXLLG Protein, AXSF Protein, growth arrest specific 6 Protein, growth arrest-specific 6 Protein, growth arrest specific 6 L homeolog Protein, growth arrest specific 6 S homeolog Protein, GAS6 Protein, gas6 Protein, gas6.L Protein, gas6.S Protein, Gas6 Protein
- 背景
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Background: GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
Synonym: AXLLG, AXLLGAXL stimulatory factor, AXSFAXL receptor tyrosine kinase ligand, Gas6, GAS-6, growth arrest-specific 6, growth arrest-specific protein 6
- 分子量
- 72.7 kDa
- UniProt
- Q14393
- 途径
- RTK signaling, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
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