EGFR Protein (Fc Tag)
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- 抗原 See all EGFR 蛋白
- EGFR (Epidermal Growth Factor Receptor (EGFR))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This EGFR protein is labelled with Fc Tag.
- 原理
- Recombinant Mouse EGFR Protein (Fc Tag)(Active)
- 序列
- Met 1-Ser 647
- 产品特性
- A DNA sequence encoding the extracellular domain of mouse EGFR (Q01279) (Met 1-Ser 647) was fused with the Fc region of human IgG1 at the C-terminus.
- 纯度
- > 90 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to bind human EGF in a functional ELISA.
- Top Product
- Discover our top product EGFR 蛋白
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Epidermal Growth Factor Receptor (EGFR) (AA 25-645) protein (His-Avi Tag)
EGFR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Epidermal Growth Factor Receptor (EGFR) protein (His-Avi Tag,Biotin)EGFR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Epidermal Growth Factor Receptor (EGFR) (AA 25-645) protein (Fc Tag)EGFR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Epidermal Growth Factor Receptor (EGFR) (AA 25-645) (Active) protein (Fc Tag)EGFR 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Epidermal Growth Factor Receptor (EGFR) (AA 25-645) (Active) protein (His tag,AVI tag,Biotin)EGFR 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Epidermal Growth Factor Receptor (EGFR) (AA 25-378) (Active) protein (His tag,AVI tag,Biotin)EGFR 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
Epidermal Growth Factor Receptor (EGFR) (AA 25-645) protein (His tag)EGFR 宿主: 猕猴 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Epidermal Growth Factor Receptor (EGFR) (AA 25-647) protein (His tag)EGFR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Epidermal Growth Factor Receptor (EGFR) protein (His tag)EGFR 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Epidermal Growth Factor Receptor (EGFR) (AA 1-405) protein (GST tag)EGFR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- EGFR (Epidermal Growth Factor Receptor (EGFR))
- 别名
- EGFR (EGFR 产品)
- 别名
- C-erb Protein, CG10079 Protein, D-EGFR Protein, D-Egf Protein, DEGFR Protein, DER Protein, DER flb Protein, DER/EGFR Protein, DER/faint little ball Protein, DER/top Protein, DER/torpedo Protein, DER1 Protein, DEgfr Protein, Degfr Protein, Der Protein, DmHD-33 Protein, Dmel\\CG10079 Protein, EFG-R Protein, EGF-R Protein, EGFR Protein, EGFr Protein, EGfr Protein, EK2-6 Protein, Egf Protein, Egf-r Protein, EgfR Protein, El Protein, Elp Protein, Elp-1 Protein, Elp-B1 Protein, Elp-B1RB1 Protein, HD-33 Protein, TOP Protein, Torpedo/DER Protein, Torpedo/Egfr Protein, c-erbB Protein, d-egf-r Protein, dEGFR Protein, dEGFR1 Protein, dEgfr Protein, der Protein, egfr Protein, flb Protein, l(2)05351 Protein, l(2)09261 Protein, l(2)57DEFa Protein, l(2)57EFa Protein, l(2)57Ea Protein, mor1 Protein, top Protein, top/DER Protein, top/flb Protein, torpedo/Egfr Protein, torpedo/egfr Protein, EGFR12 Protein, EGFR15 Protein, egfr1 Protein, Erbb2 Protein, ERBB Protein, ERBB1 Protein, HER1 Protein, PIG61 Protein, mENA Protein, ErbB-1 Protein, Errp Protein, 9030024J15Rik Protein, AI552599 Protein, Erbb Protein, Errb1 Protein, Wa5 Protein, wa-2 Protein, wa2 Protein, epidermal growth factor receptor Protein, Epidermal growth factor receptor Protein, epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) Protein, EGFR Protein, Egfr Protein, egfra Protein, egfr1 Protein, LOC5564544 Protein
- 背景
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Background: As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
Synonym: 9030024J15Rik;AI552599;Erbb;Errb1;Errp;wa-2;wa2;Wa5
- 分子量
- 96 kDa
- UniProt
- Q01279
- 途径
- NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
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