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EGFR 产品

(Epidermal Growth Factor Receptor (EGFR))

Categories

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010].

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Featured EGFR Categories

EGFR 抗体

High quality antibodies with extensive validation data.

EGFR ELISA试剂盒

Reliable ELISA kits for a wide range of species.

EGFR 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended EGFR 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IP
Validations
  • (3)
  • (2)
  • (1)
Cat. No. ABIN98862
Quantity 250 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (2)
  • (7)
Cat. No. ABIN1724824
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7426025
Quantity 100 μL
Datasheet Datasheet

Recommended EGFR ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN837930
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Cell ELISA
Validations
  • (4)
  • (5)
Cat. No. ABIN1981827
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Semi-Quantitative Cell ELISA
Validations
  • (4)
  • (5)
Cat. No. ABIN1981825
Quantity 96 tests
Datasheet Datasheet

Recommended EGFR 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274526
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274527
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274524
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our EGFR Products

Haueis, Stech, Kubick: "A Cell-free Expression Pipeline for the Generation and Functional Characterization of Nanobodies." in: Frontiers in bioengineering and biotechnology, Vol. 10, pp. 896763, (2022) (PubMed).

Lanzerstorfer, Müller, Gordiyenko, Weghuber, Niemeyer: "Highly Modular Protein Micropatterning Sheds Light on the Role of Clathrin-Mediated Endocytosis for the Quantitative Analysis of Protein-Protein Interactions in Live Cells." in: Biomolecules, Vol. 10, Issue 4, (2021) (PubMed).

Saveri, De Luca, Nisi, Pisciotta, Romano, Piscosquito, Reilly, Polke, Cavallaro, Fabrizi, Fossa, Cichero, Lombardi, Lauria, Magri, Taroni, Pareyson, Bucci: "Charcot-Marie-Tooth Type 2B: A New Phenotype Associated with a Novel RAB7A Mutation and Inhibited EGFR Degradation." in: Cells, Vol. 9, Issue 4, (2020) (PubMed).

Larios, Mercier, Roux, Gruenberg: "ALIX- and ESCRT-III-dependent sorting of tetraspanins to exosomes." in: The Journal of cell biology, Vol. 219, Issue 3, (2020) (PubMed).

Murakami, Matsumoto, Kanamori: "Constructive approach for synthesis of a functional IgG using a reconstituted cell-free protein synthesis system." in: Scientific reports, Vol. 9, Issue 1, pp. 671, (2020) (PubMed).

El-Sharief, Ammar, Belal, El-Sharief, Mohamed, Mehany, Elhag Ali, Ragab: "Design, synthesis, molecular docking and biological activity evaluation of some novel indole derivatives as potent anticancer active agents and apoptosis inducers." in: Bioorganic chemistry, Vol. 85, pp. 399-412, (2020) (PubMed).

Al-Harbi, El-Sharief, Abbas: "Synthesis and anticancer activity of bis-benzo[d][1,3]dioxol-5-yl thiourea derivatives with molecular docking study." in: Bioorganic chemistry, Vol. 90, pp. 103088, (2020) (PubMed).

Tang, Zheng, Melo, Mabardi, Castaño, Xie, Li, Kudchodkar, Wong, Jeng, Maus, Irvine: "Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery." in: Nature biotechnology, Vol. 36, Issue 8, pp. 707-716, (2019) (PubMed).

Mortensen, Skovsgaard, Okholm, Scavenius, Dupont, Rosen, Enghild, Kjems, Gothelf: "Small-Molecule Probes for Affinity-Guided Introduction of Biocompatible Handles on Metal-Binding Proteins." in: Bioconjugate chemistry, Vol. 29, Issue 9, pp. 3016-3025, (2019) (PubMed).

Hu, Wang, Jin, Liu, Cui, Sun, Li, Li, Wang, Zhen, Miao, Li: "An EGFR-targeting antibody-drug conjugate LR004-VC-MMAE: potential in esophageal squamous cell carcinoma and other malignancies." in: Molecular oncology, Vol. 13, Issue 2, pp. 246-263, (2019) (PubMed).

Synonyms and alternative names related to EGFR

epidermal growth factor receptor (EGFR), Epidermal growth factor receptor (Egfr), epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) (egfra), epidermal growth factor receptor (egfr1), epidermal growth factor receptor (LOC5564544), epidermal growth factor receptor (Egfr), 9030024J15Rik, AI552599, C-erb, c-erbB, CG10079, D-Egf, d-egf-r, D-EGFR, DEGFR, DEgfr, Degfr, dEGFR, dEgfr, dEGFR1, DER, Der, der, DER/EGFR, DER/faint little ball, DER/top, DER/torpedo, DER1, DER flb, Dmel\\CG10079, DmHD-33, EFG-R, Egf, EGF-R, Egf-r, EGFR, EGFr, EGfr, EgfR, egfr, egfr1, EGFR12, EGFR15, EK2-6, El, Elp, Elp-1, Elp-B1, Elp-B1RB1, ERBB, Erbb, ErbB-1, ERBB1, Erbb2, Errb1, Errp, flb, HD-33, HER1, l(2)05351, l(2)09261, l(2)57DEFa, l(2)57Ea, l(2)57EFa, mENA, mor1, PIG61, TOP, top, top/DER, top/flb, Torpedo/DER, Torpedo/Egfr, torpedo/Egfr, torpedo/egfr, wa-2, wa2, Wa5

Protein level used designations for EGFR

  • CG10079-PA
  • CG10079-PB
  • DER-Ellipse
  • EGF-receptor
  • EGFR
  • Egf receptor
  • Egfr-PA
  • Egfr-PB
  • drosophila epidermal growth factor receptor homologue
  • ellipse
  • ellipse torpedo
  • epidermal growth factor receptor
  • faint little ball
  • morphological defects 1
  • torpedo
  • torpedo/DER
  • erbb1a
  • avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
  • cell growth inhibiting protein 40
  • cell proliferation-inducing protein 61
  • proto-oncogene c-ErbB-1
  • receptor tyrosine-protein kinase erbB-1
  • EGFR-related peptide
  • Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1)
  • avian erythroblastic leukemia viral (v-erbB) oncogene homolog
  • epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1)
  • waved 2
  • CER
  • epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
  • egf receptor
  • receptor tyrosine kinase ErbB1
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