CST6 Protein (His tag)
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- 抗原 See all CST6 蛋白
- CST6 (Cystatin E/M (CST6))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This CST6 protein is labelled with His tag.
- 原理
- Recombinant Mouse Cystatin E/CST6 Protein (His Tag)(Active)
- 序列
- Met 1-Ala 152
- 产品特性
- A DNA sequence encoding the extracellular domain of mouse CST6 (NP_082899.1) (Met 1-Ala 152) was expressed, with a C-terminal polyhistidine tag.
- 纯度
- > 90 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to inhibit papain cleavage of a fluorogenic peptide substrate ZFR-AMC,R&D Systems, Catalog # ES009.The IC50 is < 20 nM.
- Top Product
- Discover our top product CST6 蛋白
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Cystatin E/M (CST6) (AA 61-149) protein (GST tag)
CST6 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cystatin E/M (CST6) (AA 29-149) protein (GST tag)CST6 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cystatin E/M (CST6) (AA 29-149) (Active) protein (His tag)CST6 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS Active
Cystatin E/M (CST6) protein (Myc-DYKDDDDK Tag)CST6 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CST6 (Cystatin E/M (CST6))
- 别名
- Cystatin E/CST6 (CST6 产品)
- 别名
- CST6 Protein, 1110017E11Rik Protein, N28197 Protein, ichq Protein, cystatin E/M Protein, CST6 Protein, Cst6 Protein
- 背景
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Background: Cystatin E/M, also referred to as CST6, is a member of type 2 cysteine proteinase inhibitors of the cystatin superfamily, and inhibits papain and cathepsin B. Cystatin E is a low molecular mass secreted protein existing in both a glycosylated (17 kDa) and an unglycosylated (14 kDa) form, with two characteristic intrachain disulfide bridges. Expression of cystatin M/E is found to be restricted to the epidermis, more specifically in the stratum granulosum, sweat glands, sebaceous glands, and the hair follicles. In addition to its function as a cysteine protease inhibitor, cystatin M/E also serves as a target for cross-linking by transglutaminases. Accordingly, cystatin M/E was suggested to be involved in barrier formation and maintenance. Furthermore, studies have revealed that cystatin M/E is frequently epigenetically inactivated during breast carcinogenesis, and thus be regarded as a candidate of tumour suppressor gene.
Synonym: 1110017E11Rik,ichq,N28197
- 分子量
- 15.2 kDa
- NCBI登录号
- NP_082899
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