CST6 Protein (His tag)
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- 抗原 See all CST6 蛋白
- CST6 (Cystatin E/M (CST6))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This CST6 protein is labelled with His tag.
- 原理
- Recombinant Human Cystatin E/CST6 Protein (His Tag)
- 序列
- Arg29-Met 149
- 产品特性
- Recombinant Human Cystatin E/Cystatin M is produced by our Mammalian expression system and the target gene encoding Arg29-Met149 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CST6 蛋白
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Cystatin E/M (CST6) (AA 61-149) protein (GST tag)
CST6 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cystatin E/M (CST6) (AA 29-149) protein (GST tag)CST6 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cystatin E/M (CST6) (AA 29-149) (Active) protein (His tag)CST6 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS Active
Cystatin E/M (CST6) protein (Myc-DYKDDDDK Tag)CST6 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CST6 (Cystatin E/M (CST6))
- 别名
- Cystatin E/CST6 (CST6 产品)
- 别名
- CST6 Protein, 1110017E11Rik Protein, N28197 Protein, ichq Protein, cystatin E/M Protein, CST6 Protein, Cst6 Protein
- 背景
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Background: Cystatin-M is a typical secretory protein. It is synthesized as a preprotein with a patent N-terminal signal sequence.It belongs to the cystatin family. The most widely accepted function of cystatins is that of protease inhibitors. Most cysteine proteases are confined within cells where optimal pH and redox conditions favor their enzymatic activity. Thus, the majority of intracellular cysteine proteases are inactivated by oxidizing conditions outside the cells. Among the various types of intracellular cysteine proteases, cystatins seem to target preferentially endosomal/lysosomal cysteine proteases of the papain family, such as cathepsin B, cathepsin K/O2, cathepsin L, cathepsin L2/V and cathepsin S. Another important function of Cst6 seems to be in the terminal differentiation of stratified squamous epithelial cells and in the formation of cornified envelops. Cst6 is believed to be important in fine-tuning the enzymatic activities of endosomal/lysosomal cysteine proteases such as cathepsin L, cathepsin L2/V and AEP/mammalian legumain. Deregulated activity of these proteases could lead to abnormal activation of transglutaminases and disorders in cornification.
Synonym: Cystatin-M, Cystatin-6, Cystatin-E, CST6
- 分子量
- 14.7 kDa
- UniProt
- Q15828
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