CST6 Protein (AA 29-149) (His tag)
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- 抗原 See all CST6 蛋白
- CST6 (Cystatin E/M (CST6))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 29-149
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This CST6 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MRPQERMVGE LRDLSPDDPQ VQKAAQAAVA SYNMGSNSIY YFRDTHIIKA QSQLVAGIKY FLTMEMGSTD CRKTRVTGDH VDLTTCPLAA GAQQEKLRCD FEVLVVPWQN SSQLLKHNCV QM
- 纯度
- > 90 % by SDS - PAGE
- Biological Activity Comment
- The IC50 value is < 10nM. The inhibitory function of Cystatin 6 on protease activity of papain was measured by a fluorometric assay using Z-FR-AMC at pH 7.5 at 25C.
- Top Product
- Discover our top product CST6 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Bioactivity Validated
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer( pH 8.0) containing 10 % glycerol, 1 mM DTT, 0.1M NaCl.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- CST6 (Cystatin E/M (CST6))
- 别名
- CST6 (CST6 产品)
- 别名
- CST6 Protein, 1110017E11Rik Protein, N28197 Protein, ichq Protein, cystatin E/M Protein, CST6 Protein, Cst6 Protein
- 背景
- CST6 is a member of the type 2 cystatin family. Some of the members are active cysteine protease inhibitors, while cystatin E/M moderate the inhibition of cathepsin B but is not active against cathepsin C. CST6 is secretable proteins that influence osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors, and the response to systemic inflammation. Recombinant human CST6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 15.9 kDa (142aa), confirmed by MALDI-TOF
- NCBI登录号
- NP_001314
- UniProt
- Q15828
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