KLRC1 Protein (AA 94-233) (His tag)
-
- 抗原 See all KLRC1 蛋白
- KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 94-233
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This KLRC1 protein is labelled with His tag.
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product KLRC1 蛋白
-
Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) (AA 100-233) protein (His-Avi Tag,Biotin)
KLRC1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) protein (His-Avi Tag)KLRC1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) (AA 100-219) protein (Fc Tag)KLRC1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) (AA 1-233) protein (GST tag)KLRC1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) (AA 1-70) protein (GST tag)KLRC1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) protein (His tag)KLRC1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) (AA 1-233) protein (Strep Tag)Crystallography grade KLRC1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) (AA 94-233) protein (His tag)Crystallography grade KLRC1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
-
- 抗原
- KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))
- 别名
- NKG2A (KLRC1 产品)
- 别名
- rNKG2A Protein, NKG2-A Protein, NKG2A Protein, KLRC1 Protein, CD159A Protein, NKG2 Protein, CD159a Protein, NKG2B Protein, killer cell lectin like receptor C1 Protein, NKG2-A/NKG2-B type II integral membrane protein-like Protein, killer cell lectin-like receptor subfamily C, member 3 Protein, killer cell lectin-like receptor subfamily C, member 1 Protein, Klrc1 Protein, KLRC1 Protein, NKG2A Protein, KLRC3 Protein
- 背景
- NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation, also known as KLRC1, CD159a, NK cell receptor A and NKG2-A/NKG2-B type II integral membrane protein. NKG2A marks a unique immune effector subset preferentially co-expressing the tissue-resident CD103 Molecule, but not immune checkpoint inhibitors. NKG2A blockade therapy operated through CD8 T cells, but not NK cells. The increase in NKG2A expression might be induced by IL-10, which was present at a high level in the plasma of HCC patients. Blocking IL-10 could specifically inhibit NKG2A expression in NK cells. These findings indicate that NKG2A expression is influenced by factors from cancer nests and contributes to NK cell exhaustion, suggesting that NKG2A blockade has the potential to restore immunity against liver tumors by reversing NK cell exhaustion.
- 分子量
- 17.9 kDa
- NCBI登录号
- NP_002250
-
