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KLRC1 Protein (His tag)

KLRC1 宿主: 人 宿主: 人细胞 Recombinant > 90 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7318831
发货至: 中国
  • 抗原 See all KLRC1 蛋白
    KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 13
    • 2
    • 1
    • 1
    • 1
    资源
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人细胞
    标记
    This KLRC1 protein is labelled with His tag.
    原理
    Recombinant Human CD159a/KLRC1 Protein (His Tag)(Active)
    序列
    Arg100-Leu233
    产品特性
    Recombinant Human NKG2-A/NKG2-B Type II Integral Membrane Protein is produced by our Mammalian expression system and the target gene encoding Arg100-Leu233 is expressed with a 8His tag at the N-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Immobilized Human NKG2A-His at 10μg/ml(100 μl/well) can bind Biotinylated Human CD94-His(Cat: PKSH032785). The ED50 of Human NKG2A-His is 18μg/mL.
    Top Product
    Discover our top product KLRC1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))
    别名
    CD159a/KLRC1 (KLRC1 产品)
    别名
    rNKG2A Protein, NKG2-A Protein, NKG2A Protein, KLRC1 Protein, CD159A Protein, NKG2 Protein, CD159a Protein, NKG2B Protein, killer cell lectin like receptor C1 Protein, NKG2-A/NKG2-B type II integral membrane protein-like Protein, killer cell lectin-like receptor subfamily C, member 3 Protein, killer cell lectin-like receptor subfamily C, member 1 Protein, Klrc1 Protein, KLRC1 Protein, NKG2A Protein, KLRC3 Protein
    背景

    Background: NKG2-A/NKG2-B Type II Integral Membrane Protein contains 1 C-type lectin domain and belongs to the killer cell lectin-like receptor family. The killer cell lectin-like receptor family is a group of transmembrane proteins preferentially expressed in NK cells. Members of this proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. NKG2 is expressed only in NK-cells, but not in T-cells or B-cells. It has been shown that NKG2 represents a family of related cDNA clones, designated NKG2A, NKG2B, NKG2C, and NKG2D, which encode type 2 integral membrane proteins (extracellular C-terminus) containing a C-type lectin domain. NKG2 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. NKG2A and NKG2B have been given the designation CD159a in the nomenclature of CD antigens.

    Synonym: NKG2-A/NKG2-B type II integral membrane protein, CD159 antigen-like family member A, NK cell receptor A, NKG2-A/B-activating NK receptor, CD159a, KLRC1, NKG2A

    分子量
    16.5 kDa
    UniProt
    P26715
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