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ICOSLG Protein (AA 47-279) (Fc Tag)

ICOSLG 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN6938859
发货至: 中国
  • 抗原 See all ICOSLG 蛋白
    ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 47-279
    宿主
    • 21
    • 9
    • 2
    • 1
    小鼠
    资源
    • 20
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This ICOSLG protein is labelled with Fc Tag.
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product ICOSLG 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    储存条件
    -20 °C
  • 抗原
    ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
    别名
    B7-H2 (ICOSLG 产品)
    别名
    ICOSLG Protein, AU044799 Protein, B7-H2 Protein, B7RP-1 Protein, B7h Protein, BG071784 Protein, GI50 Protein, GL50 Protein, GL50-B Protein, ICOS-L Protein, Icoslg Protein, LICOS Protein, Ly115l Protein, mKIAA0653 Protein, B7H2 Protein, B7RP1 Protein, CD275 Protein, ICOSL Protein, Icosl Protein, RGD1562791 Protein, inducible T-cell costimulator ligand Protein, icos ligand Protein, inducible T-cell co-stimulator ligand Protein, ICOSLG Protein, Icosl Protein, Icoslg Protein
    背景
    ICOS ligand (ICOSLG) is also known as B7 homolog 2 (B7-H2), B7-related protein 1 (B7RP-1) and CD antigen CD275, which belongs to the immunoglobulin superfamily and BTN/MOG family. ICOSLG contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. Isoform 1 is widely expressed, while isoform 2 is detected only in lymph nodes, leukocytes and spleen. B7-H2 is ligand for the T-cell-specific cell surface receptor ICOS. B7-H2 acts as a costimulatory signal for T-cell proliferation and cytokine secretion and induces also B-cell proliferation and differentiation into plasma cells. B7-H2 could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
    分子量
    52.7 kDa
    NCBI登录号
    NP_056605
    途径
    Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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