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ICOSLG Protein (AA 19-256) (His tag)

ICOSLG 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7273947
发货至: 中国
  • 抗原 See all ICOSLG 蛋白
    ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
    蛋白类型
    Recombinant
    产品特性
    AA 19-256
    宿主
    • 21
    • 10
    • 1
    • 1
    Cynomolgus
    资源
    • 20
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This ICOSLG protein is labelled with His tag.
    原理
    Cynomolgus B7-H2/ICOSLG Protein
    序列
    Asp19-Thr256
    产品特性
    Recombinant Cynomolgus B7-H2/ICOSLG Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp19-Thr256.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 5.42 nM as determined in SPR assay (Biacore T200). See testing image for detail.
    Top Product
    Discover our top product ICOSLG 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
    别名
    B7-H2 (ICOSLG 产品)
    别名
    ICOSLG Protein, AU044799 Protein, B7-H2 Protein, B7RP-1 Protein, B7h Protein, BG071784 Protein, GI50 Protein, GL50 Protein, GL50-B Protein, ICOS-L Protein, Icoslg Protein, LICOS Protein, Ly115l Protein, mKIAA0653 Protein, B7H2 Protein, B7RP1 Protein, CD275 Protein, ICOSL Protein, Icosl Protein, RGD1562791 Protein, inducible T-cell costimulator ligand Protein, icos ligand Protein, inducible T-cell co-stimulator ligand Protein, ICOSLG Protein, Icosl Protein, Icoslg Protein
    背景
    B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion, induces also B-cell proliferation and differentiation into plasma cells.
    分子量
    27.7 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
    NCBI登录号
    XP_005548617
    途径
    Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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