FLT3 Protein (AA 27-543) (Fc Tag)
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- 抗原 See all FLT3 蛋白
- FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 27-543
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FLT3 protein is labelled with Fc Tag.
- 序列
- AA 27-543
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product FLT3 蛋白
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Fms-Related tyrosine Kinase 3 (FLT3) (AA 27-541) protein (Fc Tag)
FLT3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Fms-Related tyrosine Kinase 3 (FLT3) (AA 28-541) protein (Fc Tag)FLT3 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fms-Related tyrosine Kinase 3 (FLT3) (AA 28-544) protein (Fc Tag)FLT3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Fms-Related tyrosine Kinase 3 (FLT3) (AA 546-993) (Active) protein (GST tag)FLT3 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Fms-Related tyrosine Kinase 3 (FLT3) (AA 571-993) (Active) protein (His-GST)FLT3 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active
Fms-Related tyrosine Kinase 3 (FLT3) protein (Fc-His Tag)FLT3 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Fms-Related tyrosine Kinase 3 (FLT3) protein (His tag)FLT3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 75 % as determined by SDS-PAGE
Fms-Related tyrosine Kinase 3 (FLT3) (AA 91-190) protein (GST tag)FLT3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fms-Related tyrosine Kinase 3 (FLT3) (AA 27-543) protein (His tag)Crystallography grade FLT3 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fms-Related tyrosine Kinase 3 (FLT3) (AA 564-993) protein (His tag)Crystallography grade FLT3 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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- 抗原
- FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
- 别名
- Flt-3 (FLT3 产品)
- 别名
- FLT3 Protein, B230315G04 Protein, CD135 Protein, Flk-2 Protein, Flk2 Protein, Flt-3 Protein, Ly72 Protein, wmfl Protein, FLK-2 Protein, FLK2 Protein, STK1 Protein, fms related tyrosine kinase 3 Protein, FMS-like tyrosine kinase 3 Protein, fms-related tyrosine kinase 3 Protein, FLT3 Protein, Flt3 Protein
- 背景
- Flt-3(Receptor-type tyrosine-protein kinase FLT3) is also known as FLK-2(Fetal liver kinase-2), STK-1(Stem cell tyrosine kinase 1), CD135. FLT3 is a cytokine receptor which belongs to the receptor tyrosine kinase class III. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.
- 分子量
- 84.8 kDa
- NCBI登录号
- NP_004110
- 途径
- RTK signaling
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