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FLT3 Protein (His tag)

FLT3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 75 % as determined by SDS-PAGE
产品编号 ABIN7320038
发货至: 中国
  • 抗原 See all FLT3 蛋白
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    蛋白类型
    Recombinant
    宿主
    • 22
    • 6
    • 1
    小鼠
    资源
    • 13
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This FLT3 protein is labelled with His tag.
    原理
    Recombinant Mouse FLT-3/FLK-2 Protein (His Tag)
    序列
    Met1-Ser544
    产品特性
    A DNA sequence encoding the mouse FLT3 (EDL05833.1) (Met1-Ser544) was expressed with a C-terminal polyhistidine tag.
    纯度
    > 75 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product FLT3 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    别名
    FLT-3/FLK-2 (FLT3 产品)
    别名
    FLT3 Protein, B230315G04 Protein, CD135 Protein, Flk-2 Protein, Flk2 Protein, Flt-3 Protein, Ly72 Protein, wmfl Protein, FLK-2 Protein, FLK2 Protein, STK1 Protein, fms related tyrosine kinase 3 Protein, FMS-like tyrosine kinase 3 Protein, fms-related tyrosine kinase 3 Protein, FLT3 Protein, Flt3 Protein
    背景

    Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD135, also known as FLT-3, FLK-2, is a member of the CD system. CD135 is an important cell surface marker recognized by specific sets of antibodies to identify the types of hematopoietic (blood) progenitors in the bone marrow and it function to differentiate hematopoietic stem cells, which are CD135 negative, from multipotent progenitors, which are CD135 positive. CD135 is a receptor tyrosine kinase typeIII for the cytokine Flt3 ligand and activat signaling through second messengers by binding to Flt3. Signaling through CD135 is important for lymphocyte development. The encoding gene CD135 is a proto-oncogene to which mutations happened will lead to cancer such as leukemia.Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

    Synonym: B230315G04;CD135;Flk-2;Flk2;Flt-3;Ly72;wmfl

    分子量
    59.5 kDa
    途径
    RTK signaling
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