FLT3 Protein (Fc-His Tag)
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- 抗原 See all FLT3 蛋白
- FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FLT3 protein is labelled with Fc-His Tag.
- 应用范围
- ELISA
- 原理
- Recombinant human FLT3 protein with C-terminal human Fc and 6xHis tag
- 特异性
- FLT3 (Asn27-Ser543) hFc (Glu99-Ala330) 6xHis tag
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- affinity purification
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product FLT3 蛋白
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Fms-Related tyrosine Kinase 3 (FLT3) (AA 27-541) protein (Fc Tag)
FLT3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Fms-Related tyrosine Kinase 3 (FLT3) (AA 28-541) protein (Fc Tag)FLT3 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fms-Related tyrosine Kinase 3 (FLT3) (AA 28-544) protein (Fc Tag)FLT3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Fms-Related tyrosine Kinase 3 (FLT3) (AA 546-993) (Active) protein (GST tag)FLT3 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Fms-Related tyrosine Kinase 3 (FLT3) (AA 571-993) (Active) protein (His-GST)FLT3 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active
Fms-Related tyrosine Kinase 3 (FLT3) protein (His tag)FLT3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 75 % as determined by SDS-PAGE
Fms-Related tyrosine Kinase 3 (FLT3) (AA 91-190) protein (GST tag)FLT3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fms-Related tyrosine Kinase 3 (FLT3) (AA 27-543) protein (His tag)Crystallography grade FLT3 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fms-Related tyrosine Kinase 3 (FLT3) (AA 564-993) protein (His tag)Crystallography grade FLT3 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fms-Related tyrosine Kinase 3 (FLT3) (AA 28-544) protein (His tag)Crystallography grade FLT3 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with deionized water
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存液
- Without preservative
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
- 别名
- FLT3 (FLT3 产品)
- 别名
- FLT3 Protein, B230315G04 Protein, CD135 Protein, Flk-2 Protein, Flk2 Protein, Flt-3 Protein, Ly72 Protein, wmfl Protein, FLK-2 Protein, FLK2 Protein, STK1 Protein, fms related tyrosine kinase 3 Protein, FMS-like tyrosine kinase 3 Protein, fms-related tyrosine kinase 3 Protein, FLT3 Protein, Flt3 Protein
- 背景
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Synonymes: Flt-3, Flk-2, STK-1, CD135, FLK2, FLT-3
Description: Flt-3(Receptor-type tyrosine-protein kinase FLT3) is also known as FLK-2(Fetal liver kinase-2), STK-1(Stem cell tyrosine kinase 1), CD135. FLT3 is a cytokine receptor which belongs to the receptor tyrosine kinase class III. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways. - 分子量
- predicted molecular mass of 125-130 kDa after removal of the signal peptide.
- 基因ID
- 2322
- UniProt
- P36888
- 途径
- RTK signaling
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