POLB Protein (AA 1-335) (His tag)
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- 抗原 See all POLB 蛋白
- POLB (Polymerase (DNA Directed), beta (POLB))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-335
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This POLB protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- POLB, 1-335aa, Human, His tag, E.coli
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product POLB 蛋白
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Polymerase (DNA Directed), beta (POLB) (AA 2-335) protein (His tag)
POLB 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Polymerase (DNA Directed), beta (POLB) (AA 1-335) protein (His tag)POLB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Polymerase (DNA Directed), beta (POLB) (AA 1-335) protein (GST tag)POLB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Polymerase (DNA Directed), beta (POLB) (AA 224-333) protein (GST tag)POLB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Polymerase (DNA Directed), beta (POLB) (Active) proteinPOLB 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % pure by SDS-PAGE analysis Func Active
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl
- 储存条件
- 4 °C
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- 抗原
- POLB (Polymerase (DNA Directed), beta (POLB))
- 别名
- POLB (POLB 产品)
- 别名
- wu:fa97a05 Protein, zgc:109924 Protein, POLB Protein, DDBDRAFT_0186152 Protein, DDBDRAFT_0215784 Protein, DDBDRAFT_0232376 Protein, DDB_0186152 Protein, DDB_0215784 Protein, DDB_0232376 Protein, A430088C08Rik Protein, polymerase (DNA directed), beta Protein, DNA polymerase beta Protein, DNA polymerase X family protein Protein, polymerase (DNA directed), beta S homeolog Protein, polb Protein, POLB Protein, polB Protein, polb.S Protein, Polb Protein
- 背景
- DNA polymerase beta, also known as POLB, belongs to the DNA polymerase type-X family. In eukaryotic cells, DNA polymerase beta (POLB) performs base excision repair (BER) required for DNA maintenance, replication, recombination, and drug resistance. POLB has two distinct domains, the larger is the polymerase domain itself, whereas a small basic N-terminal domain contains an AP lyase activity that excises the abasic sugar-phosphate residue at the strand break. POLB fills single nucleotide gaps in DNA produced by the base excision repair pathway of mammalian cells. Overexpression of POLB, as found in some human tumors, could confer an increase in spontaneous mutagenesis. Recombinant human POLB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DNA polymerase beta, DNA directed DNA polymerase beta, DNA pol beta, DNA polymerase beta, DNA polymerase beta subunit, MGC125976, Pol B, Pol beta, PolB, Polymerase (DNA directed) beta. NCBI no.: NP_002681
- 分子量
- 40.3 kDa (355aa), confirmed by MALDI-TOF
- 途径
- DNA Damage Repair
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