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DFFA Protein (AA 1-331) (His tag)

DFFA 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS-PAGE SDS
产品编号 ABIN667128
发货至: 中国
  • 抗原 See all DFFA 蛋白
    DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
    蛋白类型
    Recombinant
    产品特性
    AA 1-331
    宿主
    • 8
    • 2
    资源
    • 4
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This DFFA protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    DFFA, 1-331 aa, Human, His-tagged, Recombinant, E.coli
    纯度
    > 90 % by SDS-PAGE
    Top Product
    Discover our top product DFFA 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol 1mM DTT.
    储存条件
    4 °C
  • 抗原
    DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
    别名
    DFFA (DFFA 产品)
    别名
    DFF-45 Protein, DFF1 Protein, ICAD Protein, A330085O09Rik Protein, DFF35 Protein, Dff45 Protein, ICAD-L Protein, ICAD-S Protein, DFFA Protein, zgc:92229 Protein, DNA fragmentation factor subunit alpha Protein, DNA fragmentation factor, alpha subunit Protein, DNA fragmentation factor, 45kDa, alpha polypeptide Protein, DNA fragmentation factor, alpha polypeptide Protein, DFFA Protein, Dffa Protein, dffa Protein
    背景
    DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA, also known as DNA fragmentation factor subunit alpha, is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Recombinant DFFA protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: FF-45, DFF1, ICAD, DNA fragmentation factor subunit alpha, A330085O09Rik, ICAD L, ICAD S, DFF 1, Caspase activated deoxyribonuclease inhibitor short form, DFF 45, DFF alpha, DFF35, DFF45, DFFA, Caspase-activated deoxyribonuclease inhibitor short form, Dffa DNA fragmentation factor, alpha subunit, DNA fragmentation factor 45 kDa subunit, DNA Fragmentation Factor Alpha Subunit, DNA fragmentation factor subunit alpha, DNA fragmentation factor, 45 kD, alpha subunit, DNA fragmentation factor, 45kDa, alpha polypeptide, DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1, RP23 121D17.3, DNA fragmentation factor, alpha subunit, DNAation factor 45 kDa subunit, H13, Inhibitor of CAD, Inhibitor of Caspase Activated DNase, MGC143066, OTTHUMP00000001903, OTTHUMP00000001904,. NCBI no.: AAH07721
    分子量
    38.7 kDa (351aa), confirmed by MALDI-TOF.
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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