DFFA Protein (His tag)
-
- 抗原 See all DFFA 蛋白
- DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- 大肠杆菌（E. Coli）
- 标记
- This DFFA protein is labelled with His tag.
- 原理
- Recombinant Human DFFA Protein (His Tag)
- 序列
- Met 1-Thr331
- 产品特性
- Recombinant Human DNA Fragmentation Factor Subunit alpha is produced by our E.coli expression system and the target gene encoding Met1-Thr331 is expressed with a 6His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product DFFA 蛋白
-
DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA) (AA 1-331) protein (His tag)
DFFA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA) (AA 1-331) protein (GST tag)DFFA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA) (AA 231-331) protein (GST tag)DFFA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA) (AA 1-331) protein (Strep Tag)Crystallography grade DFFA 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA) (AA 1-331) protein (Strep Tag)Crystallography grade DFFA 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)DFFA 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- 限制
- 仅限研究用
-
- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- 抗原
- DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
- 别名
- DFFA (DFFA 产品)
- 别名
- DFF-45 Protein, DFF1 Protein, ICAD Protein, A330085O09Rik Protein, DFF35 Protein, Dff45 Protein, ICAD-L Protein, ICAD-S Protein, DFFA Protein, zgc:92229 Protein, DNA fragmentation factor subunit alpha Protein, DNA fragmentation factor, alpha subunit Protein, DNA fragmentation factor, 45kDa, alpha polypeptide Protein, DNA fragmentation factor, alpha polypeptide Protein, DFFA Protein, Dffa Protein, dffa Protein
- 背景
-
Background: DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression.
Synonym: DNA Fragmentation Factor Subunit Alpha, DNA Fragmentation Factor 45 kDa Subunit, DFF-45, Inhibitor of CAD, ICAD, DFFA, DFF1, DFF45, H13
- 分子量
- 38.7 kDa
- UniProt
- O00273
- 途径
- Apoptosis, Caspase Cascade in Apoptosis
-
