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SNCA 蛋白

SNCA 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS - PAGE SDS
产品编号 ABIN666673
发货至: 中国
  • 抗原 See all SNCA 蛋白
    SNCA (Synuclein, alpha (SNCA))
    蛋白类型
    Recombinant
    宿主
    • 25
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    资源
    • 25
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    • 3
    • 2
    大肠杆菌(E. Coli)
    应用范围
    SDS-PAGE (SDS)
    产品特性
    alpha-Synuclein, Human, Recombinant, E.coli - Lyophilized
    纯度
    > 95 % by SDS - PAGE
    过滤
    0.2 μm filtered
    Top Product
    Discover our top product SNCA 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Reconstitute in sterile distilled water at a concentration of 1mg/ml or less.
    缓冲液
    Lyophilized from a 0.2 um filtered in 20 mM Tris-HCl buffer, (pH 7.5) ,100 mM NaCl, 1mM MgCl2
    储存条件
    4 °C
  • 抗原
    SNCA (Synuclein, alpha (SNCA))
    别名
    alpha-Synuclein (SNCA 产品)
    别名
    snca Protein, MGC64356 Protein, LOC619283 Protein, NACP Protein, alphaSYN Protein, PARK1 Protein, PARK4 Protein, PD1 Protein, synuclein alpha L homeolog Protein, alpha-synuclein Protein, synuclein alpha Protein, synuclein, alpha Protein, snca.L Protein, LOC619283 Protein, SNCA Protein, Snca Protein
    背景
    Alpha-Synuclein (amino acids 1-140), an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-synuclein has been suggested to be implicated in the pathogenesis of Parkinson’s disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Moreover, recent studies have shown that alpha-synuclein has chaperone activity and that this activity is lost upon removing its C-terminal acidic tail (amino acids 96-140). Synonyms: SNCA, NACP, PARK1, alpha-Synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, Alpha synuclein, Alpha-synuclein isoform NACP140, alphaSYN, MGC105443, MGC110988, MGC127560, MGC64356, Non A beta component of AD amyloid, Non A4 component of amyloid precursor, Non-A-beta component of alzheimers disease amyloid , precursor of PARK 1, PARK 4, PARK4, Parkinson disease familial 1, PD 1, PD1, Synuclein alpha,. NCBI no.: NP_000336
    分子量
    14.4 kDa (140 aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)
    途径
    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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