DKK2 Protein (His tag)
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- 抗原 See all DKK2 蛋白
- DKK2 (Dickkopf 2 Homolog (DKK2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This DKK2 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product DKK2 蛋白
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Dickkopf 2 Homolog (DKK2) (AA 34-100) protein (His-IF2DI Tag)
DKK2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Dickkopf 2 Homolog (DKK2) (AA 34-259) protein (His tag)DKK2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS
Dickkopf 2 Homolog (DKK2) (AA 34-259) protein (His-SUMO Tag)DKK2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 说明
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Synonyms: Dickkopf-related protein 2, DKK-2
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/ml (determined by Bradford assay)
- 缓冲液
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M urea, 10% glycerol
- 储存条件
- 4 °C
- 储存方法
- Avoid repeated freezing and thawing cycles.
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- 抗原
- DKK2 (Dickkopf 2 Homolog (DKK2))
- 别名
- DKK2 (DKK2 产品)
- 别名
- DKK-2 Protein, Dkk4 Protein, zgc:171574 Protein, dickkopf WNT signaling pathway inhibitor 2 Protein, DKK2 Protein, Dkk2 Protein, dkk2 Protein
- 背景
- Dickkopf-related protein 2, also known as DKK2, belongs to the dickkopf family. DKK2 antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Recombinant human DKK2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- 分子量
- 27.6 kDa (250aa)
- NCBI登录号
- NP_055236
- 途径
- WNT signaling
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