DKK2 Protein (Fc Tag)
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- 抗原 See all DKK2 蛋白
- DKK2 (Dickkopf 2 Homolog (DKK2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This DKK2 protein is labelled with Fc Tag.
- 原理
- Recombinant Human DKK2 with C-terminal human Fc tag
- 特异性
- DKK2 (Lys34-Ile259) hFc (Glu99-Ala330)
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- affinity purification
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product DKK2 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with deionized water
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存液
- Without preservative
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- DKK2 (Dickkopf 2 Homolog (DKK2))
- 别名
- DKK2 (DKK2 产品)
- 别名
- DKK-2 Protein, Dkk4 Protein, zgc:171574 Protein, dickkopf WNT signaling pathway inhibitor 2 Protein, DKK2 Protein, Dkk2 Protein, dkk2 Protein
- 背景
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Synonymes: DKK-2
Description: This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq, Jul 2008] - 分子量
- predicted molecular mass of 51.2 kDa after removal of the signal peptide. The apparent molecular mass of DKK2-hFc is 55-70 kDa due to glycosylation.
- UniProt
- Q9UBU2
- 途径
- WNT signaling
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