PPP3CA Protein (AA 1-511) (His tag)
PPP3CA
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 85 % by SDS - PAGE
SDS
1 image
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- 抗原 See all PPP3CA 蛋白
- PPP3CA (Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-511
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This PPP3CA protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- PPP3CA, 1-511aa, Human, His tag, E.coli
- 纯度
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product PPP3CA 蛋白
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Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) (AA 1-84) protein (GST tag)
PPP3CA 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) (AA 1-511) protein (His tag)PPP3CA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 1mM EDTA, 20% glycerol
- 储存条件
- 4 °C
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- 抗原
- PPP3CA (Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA))
- 别名
- PPP3CA (PPP3CA 产品)
- 别名
- CALN Protein, CALNA Protein, CALNA1 Protein, CCN1 Protein, CNA1 Protein, PPP2B Protein, 2900074D19Rik Protein, AI841391 Protein, AW413465 Protein, CN Protein, Caln Protein, Calna Protein, CnA Protein, Calna1 Protein, calcineurin Protein, caln Protein, calna Protein, calna1 Protein, ccn1 Protein, cna1 Protein, ppp2b Protein, fj46e08 Protein, si:dkeyp-79c2.2 Protein, wu:fj46e08 Protein, ppp3ca Protein, protein phosphatase 3 catalytic subunit alpha Protein, protein phosphatase 3, catalytic subunit, alpha isoform Protein, protein phosphatase 3, catalytic subunit, alpha isozyme Protein, protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) Protein, protein phosphatase 3, catalytic subunit, alpha isozyme L homeolog Protein, serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Protein, PPP3CA Protein, Ppp3ca Protein, ppp3ca Protein, ppp3ca.L Protein, LOC100205420 Protein
- 背景
- PPP3CA, also known as Calcineurin A, is a major soluble calmodulin binding protein in the brain, a Ca2+/calmodulin dependent serine/threonine protein phosphatase, with a relatively narrow substrate specificity. It activates the T cells of the immune system and can be blocked by drugs. PPP3CA activates NFATc, a transcription factor by dephosphorylating it. The activated NFATc is then translocated into the nucleus, where it upregulates the expression of interleukin 2. Recombinant human PPP3CA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Serine/threonine-protein phosphatase 2B catalytic subunit alpha, CALN, CALNA, CALNA1, CCN1, CNA1, PPP2B. NCBI no.: NP_001124163
- 分子量
- 60.0 kDa (534aa)
- 途径
- RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Synaptic Membrane, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling
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