TNFSF4 Protein (AA 51-183) (Fc Tag)
-
- 抗原 See all TNFSF4 蛋白
- TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 51-183
-
宿主
- 猕猴
-
资源
- HEK-293 Cells
- 标记
- This TNFSF4 protein is labelled with Fc Tag.
- 序列
- AA 51-183
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 0.1 EU per μg by the LAL method.
- Top Product
- Discover our top product TNFSF4 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- 50 mM Tris, 100 mM Glycine, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
-
- 抗原
- TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))
- 别名
- OX40 Ligand (TNFSF4 产品)
- 别名
- TNFSF4 Protein, OX40L Protein, TNFRSF4 Protein, CD134L Protein, CD252 Protein, GP34 Protein, OX-40L Protein, OX4OL Protein, TXGP1 Protein, Ath-1 Protein, Ath1 Protein, Ox40l Protein, Txgp1l Protein, gp34 Protein, TNF superfamily member 4 Protein, tumor necrosis factor (ligand) superfamily, member 4 Protein, TNFSF4 Protein, Tnfsf4 Protein
- 背景
- Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L), TAX transcriptionally-activated glycoprotein 1 and CD252, which belongs to the tumor necrosis factor family. TNFSF4 is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. Furthermore, similar to other TNF superfamily members, membrane-bound OX40 Ligand (TNFSF4) exists as a homotrimer. Human TNFSF4 shares 46 % amino acid sequence identity with its mouse counterpart.
- 分子量
- 42.5 kDa
- NCBI登录号
- XP_017808006
- 途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation, Cancer Immune Checkpoints
-