TNFSF4 Protein (AA 18-111, Extracellular Domain) (DYKDDDDK Tag)
(1 reference)-
- 抗原 See all TNFSF4 蛋白
- TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 18-111, Extracellular Domain
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宿主
- 人, 小鼠
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资源
- HEK-293 Cells
- 标记
- This TNFSF4 protein is labelled with DYKDDDDK Tag.
- 应用范围
- SDS-PAGE (SDS)
- 品牌
- MegaOX40L™
- 特异性
- Binds to human and mouse OX40 [CD134].
- 交叉反应
- 人, 小鼠
- 产品特性
- The extracellular domain of mouse OX40L (aa 52-199) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag.
- 纯度
- >90 % (SDS-PAGE)
- 内毒素水平
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product TNFSF4 蛋白
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Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) (Trimer) protein (His-DYKDDDDK Tag)
TNFSF4 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) protein (mFc-His Tag)TNFSF4 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. FACS
Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) (AA 51-183) (Active) protein (His tag)HPLC verified TNFSF4 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) (AA 51-198) protein (Fc Tag)TNFSF4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) (AA 52-183) protein (His-DYKDDDDK-Strep II Tag)TNFSF4 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) protein (His tag)TNFSF4 宿主: Cynomolgus 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) (AA 1-183) protein (GST tag)TNFSF4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) (AA 1-183) protein (Strep Tag)Crystallography grade TNFSF4 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) (AA 1-198) protein (Strep Tag)Crystallography grade TNFSF4 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) (AA 51-183) protein (His tag)Crystallography grade TNFSF4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Activates T cell proliferation.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized. Contains PBS.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - 有效期
- 6 months
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: "Endothelial cell co-stimulation through OX40 augments and prolongs T cell cytokine synthesis by stabilization of cytokine mRNA." in: International immunology, Vol. 17, Issue 6, pp. 737-47, (2005) (PubMed).
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: "Endothelial cell co-stimulation through OX40 augments and prolongs T cell cytokine synthesis by stabilization of cytokine mRNA." in: International immunology, Vol. 17, Issue 6, pp. 737-47, (2005) (PubMed).
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- 抗原
- TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))
- 别名
- MegaOX40L (TNFSF4 产品)
- 别名
- TNFSF4 Protein, OX40L Protein, TNFRSF4 Protein, CD134L Protein, CD252 Protein, GP34 Protein, OX-40L Protein, OX4OL Protein, TXGP1 Protein, Ath-1 Protein, Ath1 Protein, Ox40l Protein, Txgp1l Protein, gp34 Protein, TNF superfamily member 4 Protein, tumor necrosis factor (ligand) superfamily, member 4 Protein, TNFSF4 Protein, Tnfsf4 Protein
- 背景
- OX40L is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium. MultimericOX40L is a high activity construct in which two trimeric OX40L ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively activates T cell proliferation.
- 分子量
- ~40kDa (SDS-PAGE)
- UniProt
- P43488
- 途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation, Cancer Immune Checkpoints
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