IL-6 Receptor Protein (AA 20-357) (Fc Tag)
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- 抗原 See all IL-6 Receptor (IL6R) 蛋白
- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
- 蛋白类型
- Recombinant
- 产品特性
- AA 20-357
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宿主
- 小鼠
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资源
- CHO Cells
- 标记
- This IL-6 Receptor protein is labelled with Fc Tag.
- 原理
- IL-6R (mouse):Fc (mouse) (rec.)
- 特异性
- The extracellular domain of mouse IL-6R (aa 20-357) is fused to the N-terminus of the Fc region of mouse IgG2a.
- 产品特性
- Protein. The extracellular domain of mouse IL-6R (aa 20-357) is fused to the N-terminus of the Fc region of mouse IgG2a. Source: CHO cells. Endotoxin content: <0.06EU/μg protein (LAL test, Lonza). Lyophilized from 0.2μm-filtered solution in PBS. Purity: >98 % (SDS-PAGE). Interleukin 6 receptor (IL-6R, CD126) is a type I cytokine receptor, which is a protein complex consisting of an IL-6 receptor subunit (IL-6R) and interleukin 6 signal transducer glycoprotein 130 (gp130). It is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. Dysregulated production of IL-6 and IL-6R are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer.
- 纯度
- >98 % (SDS-PAGE)
- 内毒素水平
- <0.06EU/μg protein (LAL test, Lonza).
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA.
- Top Product
- Discover our top product IL6R 蛋白
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Interleukin 6 Receptor (IL6R) protein (His tag)
IL6R 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Interleukin 6 Receptor (IL6R) (AA 229-468) protein (His-IF2DI Tag)IL6R 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 6 Receptor (IL6R) (AA 21-120) protein (GST tag)IL6R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 6 Receptor (IL6R) (AA 1-468) protein (GST tag)IL6R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 6 Receptor (IL6R) (AA 20-365) protein (His tag)Crystallography grade IL6R 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 6 Receptor (IL6R) (AA 20-468) protein (rho-1D4 tag)Crystallography grade IL6R 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized from 0.2μm-filtered solution in PBS.
- 注意事项
- Avoid freeze/thaw cycles.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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- 抗原
- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
- 别名
- IL-6R (IL6R 产品)
- 别名
- IL6R Protein, il-6ra Protein, CD126 Protein, IL-6R-1 Protein, IL-6RA Protein, IL6Q Protein, IL6RA Protein, IL6RQ Protein, gp80 Protein, IL6R1 Protein, Il6ra Protein, IL-6Ralpha Protein, IL-6R Protein, Il6r Protein, interleukin 6 receptor Protein, interleukin 6 receptor, alpha Protein, IL6R Protein, il6r Protein, Il6r Protein, Il6ra Protein
- 背景
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Alternate Names/Synonyms: Interleukin-6 Receptor Subunit alpha, IL6RA, CD126
Product Description: Interleukin 6 receptor (IL-6R, CD126) is a type I cytokine receptor, which is a protein complex consisting of an IL-6 receptor subunit (IL-6R) and interleukin 6 signal transducer glycoprotein 130 (gp130). It is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. Dysregulated production of IL-6 and IL-6R are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer.
- 途径
- JAK/STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
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