IL-6 Receptor Protein (His tag)
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- 抗原 See all IL-6 Receptor (IL6R) 蛋白
- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL-6 Receptor protein is labelled with His tag.
- 应用范围
- ELISA
- 原理
- Recombinant Human IL6R Protein with C-terminal 6xHis tag
- 特异性
- IL6R (Leu20-Pro365) 6xHis tag
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- affinity purification
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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Interleukin 6 Receptor (IL6R) (AA 229-468) protein (His-IF2DI Tag)
IL6R 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 6 Receptor (IL6R) (AA 21-120) protein (GST tag)IL6R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 6 Receptor (IL6R) (AA 1-468) protein (GST tag)IL6R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 6 Receptor (IL6R) (AA 20-365) protein (His tag)Crystallography grade IL6R 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 6 Receptor (IL6R) (AA 20-468) protein (rho-1D4 tag)Crystallography grade IL6R 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with deionized water
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存液
- Without preservative
- 储存条件
- -20 °C,-80 °C
- 有效期
- 12 months
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- 抗原
- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
- 别名
- IL6R (IL6R 产品)
- 别名
- IL6R Protein, il-6ra Protein, CD126 Protein, IL-6R-1 Protein, IL-6RA Protein, IL6Q Protein, IL6RA Protein, IL6RQ Protein, gp80 Protein, IL6R1 Protein, Il6ra Protein, IL-6Ralpha Protein, IL-6R Protein, Il6r Protein, interleukin 6 receptor Protein, interleukin 6 receptor, alpha Protein, IL6R Protein, il6r Protein, Il6r Protein, Il6ra Protein
- 背景
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Synonymes: CD126, gp80, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ
Description: This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9. - 分子量
- predicted molecular mass of 39.4 kDa after removal of the signal peptide.The apparent molecular mass of IL6R-His is 55-70 kDa due to glycosylation.
- 基因ID
- 3570
- UniProt
- P08887
- 途径
- JAK/STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
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