ICOSLG Protein (AA 29-450) (His tag)
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- 抗原 See all ICOSLG 蛋白
- ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
- 蛋白类型
- Recombinant
- 产品特性
- AA 29-450
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ICOSLG protein is labelled with His tag.
- 原理
- CD275 [B7-H2] (human) (rec.) (His)
- 特异性
- The extracellular domain of human CD275 [B7-H2] (aa 19-256) is fused at the C-terminus to a His-tag.
- 产品特性
- Protein. The extracellular domain of human CD275 [B7-H2] (aa 19-256) is fused at the C-terminus to a His-tag. Source: HEK 293 cells. Endotoxin content: <0.01EU/μg protein (LAL test, Lonza). Lyophilized from 0.2μm-filtered solution in PBS. Purity: >95 % (SDS-PAGE). Human B7-H2 is a member of the growing B7 family of immune costimulatory proteins. Other family members include B7-1, B7-2, B7-H1 (PD-L1), PD-L2 and B7-H3. B7 proteins are members of the immunoglobulin (Ig) superfamily, the extracellular domains contain 2 Ig-like domains and all members have short cytoplasmic domains. B7-H2 has been identified as the ligand for ICOS, a member of the CD28 family of costimulatory receptors. Human B7-H2 is expressed constitutively on resting B cells, dendritic cells and at low levels on monocytes. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
- 纯度
- >95 % (SDS-PAGE)
- 内毒素水平
- <0.01EU/μg protein (LAL test, Lonza).
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA.
- Top Product
- Discover our top product ICOSLG 蛋白
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Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 19-258) protein (His-Avi Tag)
ICOSLG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 19-258) protein (Fc Tag)ICOSLG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator Ligand (ICOSLG) protein (His-Avi Tag,Biotin)ICOSLG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 47-279) protein (His tag)ICOSLG 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 19-256) protein (His tag)ICOSLG 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 18-135) protein (His-DYKDDDDK-Strep II Tag)ICOSLG 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 18-256) protein (His-DYKDDDDK-Strep II Tag)ICOSLG 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Inducible T-Cell Co-Stimulator Ligand (ICOSLG) protein (mFc-His Tag)ICOSLG 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. FACS
Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 20-302) protein (GST tag)ICOSLG 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (Active) protein (His tag,Fc Tag)ICOSLG 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized from 0.2μm-filtered solution in PBS.
- 注意事项
- Avoid freeze/thaw cycles. PBS containing at least 0.1 % BSA should be used for further dilutions.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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- 抗原
- ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
- 别名
- CD275 [B7-H2] (ICOSLG 产品)
- 别名
- ICOSLG Protein, AU044799 Protein, B7-H2 Protein, B7RP-1 Protein, B7h Protein, BG071784 Protein, GI50 Protein, GL50 Protein, GL50-B Protein, ICOS-L Protein, Icoslg Protein, LICOS Protein, Ly115l Protein, mKIAA0653 Protein, B7H2 Protein, B7RP1 Protein, CD275 Protein, ICOSL Protein, Icosl Protein, RGD1562791 Protein, inducible T-cell costimulator ligand Protein, icos ligand Protein, inducible T-cell co-stimulator ligand Protein, ICOSLG Protein, Icosl Protein, Icoslg Protein
- 背景
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Alternate Names/Synonyms: B7-H2, ICOS Ligand, B7-like Protein Gl50, B7RP-1
Product Description: Human B7-H2 is a member of the growing B7 family of immune costimulatory proteins. Other family members include B7-1, B7-2, B7-H1 (PD-L1), PD-L2 and B7-H3. B7 proteins are members of the immunoglobulin (Ig) superfamily, the extracellular domains contain 2 Ig-like domains and all members have short cytoplasmic domains. B7-H2 has been identified as the ligand for ICOS, a member of the CD28 family of costimulatory receptors. Human B7-H2 is expressed constitutively on resting B cells, dendritic cells and at low levels on monocytes. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
- 分子量
- ~40kDa (SDS-PAGE)
- NCBI登录号
- NP_056074
- 途径
- Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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